{ "article": { "LEGIARTI000006800060": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5118", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1988-05-08", "DATE_DEBUT": "1956-11-28" } }, "META_COMMUN": { "ID": "LEGIARTI000006800060", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800060.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5118R0000XXAA" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "JORFTEXT000000518702", "#text": "Décret 72-1062 1972-11-21 ART. 1 JORF 30 novembre 1972", "@sens": "source", "@cidtexte": "JORFTEXT000000518702", "@numtexte": "72-1062", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-11-21" }, { "@id": "JORFTEXT000000337674", "#text": "Décret 79-256 1979-03-21 art. 1 JORF 31 mars 1979", "@sens": "source", "@cidtexte": "JORFTEXT000000337674", "@numtexte": "79-256", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1979-03-21" }, { "@id": "LEGIARTI000006718724", "@num": "1", "#text": "Arrêté du 5 septembre 1989 - art. 1 (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000840430", "@nortexte": "SPSM8901858A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1989-09-05" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006800059", "@num": "R5117", "#text": "Code de la santé publique - art. R5117 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914726", "@num": "R5121-11", "#text": "Code de la santé publique - art. R5121-11 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914727", "@num": "R5121-11", "#text": "Code de la santé publique - art. R5121-11 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800097", "@num": "R5124", "#text": "Code de la santé publique - art. R5124 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800105", "@num": "R5125", "#text": "Code de la santé publique - art. R5125 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800147", "@num": "R5133", "#text": "Code de la santé publique - art. R5133 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Décret 60-326 1960-04-05 ART. 10 JORF 7 avril 1960", "@sens": "source", "@typelien": "MODIFICATION" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187146", "@fin": "1994-01-09", "#text": "Paragraphe 1 : Expérimentation des médicaments.", "@debut": "1956-11-28" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800060", "@fin": "1988-05-08", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800061", "@fin": "1990-09-29", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800062", "@fin": "1993-08-07", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800063", "@fin": "1994-01-09", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800064", "@fin": "1998-02-13", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800065", "@fin": "1999-03-05", "@num": "R5118", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800066", "@fin": "2004-08-08", "@num": "R5118", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Le ministre chargé de la santé fixe par arrêté les protocoles déterminant les normes et méthodes applicables à l'expérimentation des médicaments.
\n
" } }, "LEGIARTI000006718724": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "1", "ETAT": "VIGUEUR", "TYPE": "AUTONOME", "DATE_FIN": "2999-01-01", "DATE_DEBUT": "1989-09-19" } }, "META_COMMUN": { "ID": "LEGIARTI000006718724", "URL": "article/LEGI/ARTI/00/00/06/71/87/LEGIARTI000006718724.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SPIIXXXXXXX001AAXXXXXXAA" } }, "LIENS": { "LIEN": [ { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" } ] }, "CONTEXTE": { "TEXTE": { "@cid": "JORFTEXT000000840430", "@nor": "SPSM8901858A", "@nature": "ARRETE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Arrêté du 5 septembre 1989 RELATIF AUX BONNES PRATIQUES DE LABORATOIRE", "@debut": "2999-01-01", "@id_txt": "JORFTEXT000000840430", "@c_titre_court": "Arrêté du 5 septembre 1989" }, { "@fin": "2999-01-01", "#text": "Arrêté du 5 septembre 1989 relatif aux bonnes pratiques de laboratoire", "@debut": "1989-09-19", "@id_txt": "LEGITEXT000006059178", "@c_titre_court": "Arrêté du 5 septembre 1989" } ], "@date_publi": "1989-09-19", "@date_signature": "1989-09-05" } }, "VERSIONS": { "VERSION": [ { "@etat": "VIGUEUR", "LIEN_ART": { "@id": "LEGIARTI000006718724", "@fin": "2999-01-01", "@num": "1", "@etat": "VIGUEUR", "@debut": "1989-09-19", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Les principes mentionnés au deuxième alinéa de l'article R. 5118 sont publiés au Bulletin officiel du ministère chargé de la santé sous forme d'instructions relatives aux bonnes pratiques de laboratoire (B.P.L.) dans le domaine de la toxicologie expérimentale.
\n
" } }, "LEGIARTI000006732698": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "ANNEXE", "ETAT": "VIGUEUR", "TYPE": "AUTONOME", "DATE_FIN": "2999-01-01", "DATE_DEBUT": "1996-12-29" } }, "META_COMMUN": { "ID": "LEGIARTI000006732698", "URL": "article/LEGI/ARTI/00/00/06/73/26/LEGIARTI000006732698.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SQIVUXXXXXXA04AAXXXXXXAA" } }, "LIENS": { "LIEN": [ { "#text": "Arrêté 1996-12-09 annexe", "@sens": "source", "@typelien": "CITATION" }, { "@id": "JORFTEXT000000508831", "#text": "Loi 88-1138 1988-12-20", "@sens": "source", "@cidtexte": "JORFTEXT000000508831", "@nortexte": "SPSX8810045L", "@numtexte": "88-1138", "@typelien": "CITATION", "@naturetexte": "LOI", "@datesignatexte": "1988-12-20" }, { "@id": "LEGIARTI000006692624", "@num": "L209-12", "#text": "Code de la santé publique - art. L209-12 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693701", "@num": "L601", "#text": "Code de la santé publique - art. L601 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693765", "@num": "L601-6", "#text": "Code de la santé publique - art. L601-6 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798938", "@num": "R2029", "#text": "Code de la santé publique - art. R2029 (Ab)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800076", "@num": "R5120", "#text": "Code de la santé publique - art. R5120 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800086", "@num": "R5122", "#text": "Code de la santé publique - art. R5122 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800283", "@num": "R5128-2", "#text": "Code de la santé publique - art. R5128-2 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800138", "@num": "R5132", "#text": "Code de la santé publique - art. R5132 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800141", "@num": "R5133", "#text": "Code de la santé publique - art. R5133 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006126724", "@fin": "2999-01-01", "#text": "QUATRIEME PARTIE : Documentation clinique.", "@debut": "1996-12-29" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006105791", "@fin": "2999-01-01", "#text": "Annexes", "@debut": "1996-12-29" } ] }, "@cid": "JORFTEXT000000747887", "@nor": "TASP9624370A", "@nature": "ARRETE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Arrêté du 9 décembre 1996 fixant les normes et protocoles applicables aux essais analytiques, aux essais toxicologiques et pharmacologiques ainsi qu'à la documentation clinique auxquels sont soumis les médicaments ou produits mentionnés à l'article L. 601 du code de la santé publique", "@debut": "2999-01-01", "@id_txt": "JORFTEXT000000747887", "@c_titre_court": "Arrêté du 9 décembre 1996" }, { "@fin": "2999-01-01", "#text": "Arrêté du 9 décembre 1996 fixant les normes et protocoles applicables aux essais analytiques, aux essais toxicologiques et pharmacologiques ainsi qu'à la documentation clinique auxquels sont soumis les médicaments ou produits mentionnés à l'article L. 601 du code de la santé publique", "@debut": "1996-12-29", "@id_txt": "LEGITEXT000005622457", "@c_titre_court": "Arrêté du 9 décembre 1996" } ], "@ministere": "MINISTERE DU TRAVAIL ET DES AFFAIRES SOCIALES", "@date_publi": "1996-12-29", "@date_signature": "1996-12-09", "@num_parution_jo": "0303" } }, "VERSIONS": { "VERSION": [ { "@etat": "VIGUEUR", "LIEN_ART": { "@id": "LEGIARTI000006732698", "@fin": "2999-01-01", "@num": "ANNEXE", "@etat": "VIGUEUR", "@debut": "1996-12-29", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Les renseignements et documents qui doivent être joints à la demande d'autorisation de mise sur le marché mentionnée à l'article L. 601 du code de la santé publique sont donnés conformément aux prescriptions suivantes.
\n
On entend par essai clinique tout essai systématique d'un médicament chez l'homme, qu'il s'agisse de volontaires malades ou sains, afin d'en mettre en évidence ou d'en vérifier les effets, d'identifier tout effet indésirable et d'en étudier l'absorption, la distribution, le métabolisme et l'excrétion pour en établir l'efficacité et la sécurité d'emploi.
\n
La demande d'autorisation de mise sur le marché est appréciée sur la base des essais cliniques, y compris des essais de pharmacologie clinique, portant sur l'efficacité et l'innocuité dans les conditions normales d'emploi du produit en question, compte tenu de ses indications thérapeutiques chez l'homme. Les bénéfices thérapeutiques doivent prévaloir sur les risques potentiels.
\n
\nA. - Exigences générales
\n
Les renseignements cliniques à fournir en vertu de l'article R. 5132 du code de la santé publique doivent permettre de déterminer si le médicament répond aux critères de délivrance d'une autorisation de mise sur le marché. C'est pourquoi les résultats de tous les essais effectués, aussi bien favorables que défavorables, doivent être communiqués.
\n
Les essais cliniques doivent toujours se fonder sur le dernier état des connaissances scientifiques et être précédés d'essais pharmacologiques et toxicologiques suffisants, effectués sur l'animal conformément aux dispositions de la troisième partie de la présente annexe.
\n
L'investigateur doit prendre connaissance des conclusions des études pharmacologiques et toxicologiques. Par conséquent, le promoteur doit lui fournir au minimum la brochure pour l'investigateur comportant toutes les informations pertinentes connues avant le début d'un essai clinique : les données chimiques, pharmaceutiques et biologiques, les données toxicologiques, pharmacocinétiques et pharmacodynamiques chez les animaux et les résultats d'essais menés chez l'homme antérieurement, avec suffisamment d'informations pour justifier le type, la taille et la durée de l'essai proposé ; sur demande, les rapports pharmacologique et toxicologique complets doivent être fournis. Pour les essais conduits en France, les dispositions conjuguées des articles R. 2029 et R. 5122 du code de la santé publique définissent les informations communiquées à l'investigateur préalablement à l'essai clinique.
\n
Pour les médicaments contenant des produits biologiques ou dont la fabrication fait appel à de tels produits, tous les moyens disponibles doivent être mis en oeuvre afin d'assurer l'absence de transmission d'agents infectieux avant le commencement de l'essai. Pour les essais conduits en France, il est indispensable de disposer de données concernant la garantie des sources de tissus et de liquides corporels d'origine humaine ou animale, l'identification des étapes du procédé de fabrication-extraction-purification de nature à éliminer-inactiver les virus et les agents de contamination non conventionnels et la mise en oeuvre d'études de validation prouvant l'efficacité desdites étapes (avis concernant les médicaments contenant des produits d'origine biologique ou dont la fabrication fait appel à de tels produits, J.O. du 23 février 1993). Ces données sont à considérer au regard des connaissances scientifiques du moment et sont obligatoirement à actualiser en fonction de l'évolution des connaissances scientifiques.
\n
\nB. - Conduite des essais
\n
1. Bonnes pratiques cliniques.
\n 1.1. Toutes les phases des essais cliniques, y compris les essais de biodisponibilité et de bioéquivalence, doivent être planifiées, mises en oeuvre et faire l'objet de rapports conformément aux bonnes pratiques cliniques mentionnées à l'article R. 5118 du code de la santé publique.
\n 1.2. Tous les essais cliniques doivent être réalisés conformément aux principes éthiques prévus par la version en vigueur de la déclaration d'Helsinki. En principe, le consentement éclairé doit être donné librement par chaque sujet participant à un essai clinique et consigné.
\n
Le protocole de l'essai clinique (y compris sa conception du point de vue statistique), les techniques mises en oeuvre et la documentation sont soumis pour avis au comité d'éthique approprié. Les essais ne peuvent commencer avant que ce comité n'ait émis son avis par écrit.
\n
Pour les essais ou la partie des essais réalisés en France, la loi n° 88-1138 du 20 décembre 1988 modifiée et les textes réglementaires pris pour son application définissent les conditions de protection des personnes qui se prêtent à ces essais cliniques.
\n 1.3. Dans le cadre d'un essai clinique, il est nécessaire de formaliser a priori et par écrit l'organisation, la conduite, le recueil des données, les documents, les procédures de vérification et l'exploitation des résultats.
\n 1.4. Dans le cas des médicaments radiopharmaceutiques, les essais cliniques sont placés sous la responsabilité d'un médecin autorisé à utiliser des radionucléides à des fins médicales.
\n
2. Archivage.
\n
Le demandeur prend les mesures nécessaires à l'archivage de la documentation de l'ensemble des essais conduits sur le médicament. La conservation des documents pour chaque essai chez l'investigateur, le promoteur et toutes les parties intervenant dans l'essai doit être conforme aux bonnes pratiques cliniques mentionnées à l'article R. 5118 du code de la santé publique.
\n
Tout changement de propriété des données doit être documenté.
\n
Conformément aux dispositions des textes législatifs et réglementaires en vigueur, le promoteur, l'investigateur et tout autre intervenant de l'essai doivent mettre à disposition des autorités compétentes, dans les conditions prévues par ces textes, si requis, toutes les données concernant l'essai clinique et les médicaments destinés à cet essai.
\n
\n C. - Présentation des résultats
\n
1. Les renseignements fournis concernant chaque essai clinique doivent être suffisamment détaillés pour permettre un jugement objectif et comprendre :
\n
- le protocole, y compris la justification, les objectifs, les méthodes statistiques et la méthodologie de l'essai, de même que les conditions dans lesquelles l'essai a été réalisé et géré ainsi que les renseignements relatifs au médicament étudié. Pour les essais ou les parties des essais réalisés en France, sera indiquée dans le rapport la date d'enregistrement de l'essai par l'Agence du médicament et sera joint l'avis du comité consultatif de protection des personnes dans la recherche biomédicale prévu à l'article L. 209-12 du code de la santé publique ;
\n
- le(s) certificat(s) d'audit s'il(s) est (sont) disponible(s) ;
\n
- la liste des investigateurs mentionnant les nom, adresse, fonctions, titres, activités hospitalières de chacun d'eux et le lieu où l'essai a été réalisé ;
\n
- le rapport final, signé par l'investigateur et, en cas d'essai multicentrique, par tous les investigateurs, ou à défaut, par l'investigateur coordonnateur. Ce rapport comprend les tableaux de données individuelles des personnes se prêtant à l'essai, dans le respect des règles de confidentialité prévues à l'article R. 5120 du code de la santé publique.
\n
2. Les renseignements relatifs aux essais cliniques cités ci-dessus sont transmis aux autorités compétentes. Cependant, en accord avec les autorités compétentes, le demandeur peut omettre une partie de cette information. La documentation complète est alors mise à la disposition des autorités compétentes sur demande.
\n
3. Les observations cliniques doivent être résumées pour chaque essai, en indiquant :
\n
a) Le nombre des personnes traitées, avec répartition par sexe ;
\n
b) La sélection et la composition par âge des groupes de traitement ;
\n
c) Le nombre de personnes traitées ayant interrompu prématurément les essais ainsi que les motifs de cette interruption ;
\n
d) Lorsque des essais comparatifs ont été effectués dans les conditions mentionnées ci-dessus, si le groupe témoin :
\n
- n'a été soumis à aucune thérapeutique ;
\n
- a reçu un placebo ;
\n
- a reçu un médicament de référence ;
\n
- a reçu un traitement autre que médicamenteux ;
\n
e) La fréquence des effets indésirables constatés :
\n
f) Des précisions sur les personnes présentant des susceptibilités particulières (personnes âgées, enfants, femmes enceintes ou en période d'activité génitale) ou dont l'état physiologique ou pathologique est à prendre en considération ;
\n
g) Des paramètres ou critères d'évaluation de l'efficacité et les résultats exprimés en fonction de ces paramètres ;
\n
h) Une appréciation statistique des résultats, lorsqu'elle est impliquée par la méthodologie des essais et la variabilité.
\n
4. L'investigateur doit, dans ses conclusions de l'essai, se prononcer sur l'innocuité dans les conditions normales d'emploi et de la tolérance, l'efficacité du produit avec toutes précisions utiles sur les indications et contre-indications, la posologie et la durée moyenne du traitement, ainsi que, le cas échéant, les précautions particulières d'emploi et les signes cliniques du surdosage. Dans son rapport sur un essai multicentrique, l'investigateur coordonnateur doit, dans ses conclusions, se prononcer sur la sécurité et l'efficacité du médicament étudié au nom de tous les centres impliqués.
\n
5. En outre, l'investigateur doit toujours signaler les observations faites sur :
\n
a) Les phénomènes éventuels d'accoutumance, de toxicomanie ou de sevrage ;
\n
b) Les interactions constatées avec d'autres médicaments administrés simultanément ;
\n
c) Les critères sur la base desquels certains patients ont été exclus des essais ;
\n
d) Les décès qui ont lieu pendant l'essai ou la période de suivi.
\n
6. Les renseignements concernant une nouvelle association médicamenteuse doivent être identiques à ceux prévus pour un nouveau médicament et justifier l'association par rapport à l'innocuité et à l'efficacité.
\n
7. L'absence totale ou partielle de données doit être justifiée. Dans le cas où des effets imprévus apparaissent au cours des essais cliniques, de nouveaux essais non cliniques, toxicologiques et pharmacologiques doivent être réalisés et analysés en conséquence.
\n
Si le médicament est destiné à une administration prolongée, des renseignements doivent être fournis sur les éventuelles modifications de la pharmacologie après des administrations répétées et sur la détermination de la posologie pour une administration prolongée.
\n
\nD. - Pharmacologie clinique
\n
1. Pharmacodynamie.
\n
L'action pharmacodynamique corrélée à l'efficacité doit être démontrée, et comprend notamment :
\n
- la relation dose-effet et son évolution avec le temps ;
\n
- la justification de la posologie et des conditions d'administration ;
\n
- le mode d'action, si possible.
\n
Les actions pharmacodynamiques non corrélées à l'efficacité doivent être décrites.
\n
La démonstration d'un effet pharmacodynamique chez l'homme ne suffit pas à elle seule à justifier des conclusions quant à un éventuel effet thérapeutique.
\n
2. Pharmacocinétique.
\n
Les caractéristiques pharmacocinétiques suivantes doivent être décrites :
\n
- absorption (vitesse et intensité) ;
\n
- distribution ;
\n
- métabolisme ;
\n
- excrétion.
\n
Il faut décrire les caractéristiques importantes au plan clinique, telles que les implications des données cinétiques sur la posologie, notamment pour les patients à risque, et les différences entre l'homme et les espèces animales utilisées pour les études précliniques.
\n
3. Interactions.
\n
Si le médicament doit être couramment utilisé simultanément avec d'autres médicaments, des renseignements doivent être donnés sur les essais d'administration conjointe effectués pour mettre en évidence d'éventuelles modifications de l'action pharmacologique.
\n
S'il existe des interactions pharmacodynamiques ou pharmacocinétiques entre la substance et d'autres médicaments ou des substances comme l'alcool, la caféine, le tabac ou la nicotine, susceptibles d'être pris simultanément, ou si de telles interactions sont vraisemblables, elles doivent être décrites et discutées, en particulier sous l'angle de la pertinence clinique et des interactions médicamenteuses figurant dans le résumé des caractéristiques du produit, établi conformément à l'article R. 5128-2 du code de la santé publique.
\n
\nE. - Biodisponibilité-bioéquivalence
\n
L'évaluation de la biodisponibilité doit être entreprise dans tous les cas où elle s'impose, par exemple lorsque la dose thérapeutique est proche de la dose toxique ou que les essais précédents ont fait apparaître des anomalies pouvant être en relation avec des propriétés pharmacocinétiques, par exemple une absorption variable.
\n
En outre, l'évaluation de la biodisponibilité sera entreprise :
\n
- si cela s'avère nécessaire pour démontrer la bioéquivalence pour les spécialités mentionnées au c de l'article R. 5133 du code de la santé publique ;
\n
- pour démontrer la bioéquivalence pour les spécialités génériques définies à l'article L. 601-6 du code de la santé publique, sauf exonération dans les cas prévus par le décret mentionné au dernier alinéa du même article.
\n
\nF. - Efficacité et sécurité
\n
1. D'une manière générale, les essais cliniques doivent être effectués sous forme d'essais comparatifs et, si possible, randomisés ; toute autre manière de procéder doit être justifiée. Le traitement attribué au groupe témoin peut varier selon les cas : ce choix peut être influencé par des considérations d'ordre éthique. Ainsi, il peut parfois être plus intéressant de comparer l'efficacité d'un nouveau médicament à celui d'un médicament dont la valeur thérapeutique est déjà communément connue, plutôt qu'à l'effet d'un placebo.
\n
Dans la mesure du possible, et en particulier lorsque le critère d'évaluation est d'appréciation subjective, il faut prendre des mesures pour éviter les biais, notamment des méthodes de randomisation et de double insu.
\n
2. Le protocole de l'essai doit comporter la description détaillée des méthodes statistiques mises en oeuvre, le nombre de personnes qui se prêtent à l'essai et les raisons de leur participation (y compris le calcul de la valeur statistique de l'essai), le niveau de signification utilisé et la description de l'unité de calcul statistique. Les mesures prises pour éviter les biais, notamment les méthodes de randomisation, sont documentées. Le recours à un grand nombre de patients au cours d'un essai ne doit en aucun cas être considéré comme pouvant remplacer un essai contrôlé bien exécuté.
\n
3. Des déclarations cliniques sur l'efficacité et sur l'innocuité d'un médicament dans les conditions normales d'emploi, qui ne sont pas étayées scientifiquement, ne peuvent être acceptées comme preuves valables.
\n
4. La valeur des renseignements concernant l'efficacité et l'innocuité d'un médicament dans les conditions normales d'emploi est fortement rehaussée si ces renseignements émanent de plusieurs investigateurs compétents et indépendants.
\n
5. Pour les vaccins et sérums, l'état immunologique et l'âge de la population participant à l'essai et l'épidémiologie locale sont d'une importance capitale ; ils doivent être suivis durant l'essai et décrits en détail.
\n
Pour les vaccins vivants atténués, les essais cliniques doivent être conçus de manière à mettre en évidence une transmission potentielle de l'agent immunisant de personnes vaccinées à des personnes non vaccinées. Si la transmission est possible, la stabilité génotypique et phénotypique de l'agent immunisant doit être étudiée.
\n
Pour les vaccins et les produits allergènes, le suivi comprend des tests immunologiques appropriés, le cas échéant des titrages d'anticorps.
\n
6. La pertinence des différents essais pour évaluer la sécurité et la validité des méthodes d'évaluation doit être discutée dans le rapport d'expert.
\n
7. Les événements indésirables, y compris les résultats anormaux d'analyse de biologie médicale, doivent être présentés séparément pour chaque sujet et seront discutés, notamment :
\n
- de manière globale et
\n
- en fonction de la nature, de la gravité et de la causalité des effets.
\n
8. Une évaluation critique de la sécurité relative tenant compte des effets indésirables doit être effectuée à propos :
\n
- de l'affection traitée ;
\n
- des autres approches thérapeutiques ;
\n
- des caractéristiques particulières des sous-groupe de patients ;
\n
- des données précliniques de toxicologie et de pharmacologie.
\n
9. Des recommandations doivent être faites quant aux conditions d'utilisation dans le but de diminuer l'incidence des effets indésirables.
\n
\nG. - Expérience après mise sur le marché
\n
1. Si le médicament est déjà autorisé dans d'autres pays, les informations sur les effets indésirables du médicament en question et de médicaments contenant le ou les mêmes principes actifs doivent être fournies, si possible avec les chiffres de vente dans ces pays. Des informations provenant d'études à l'échelle mondiale relatives à l'innocuité du médicament sont également fournies.
\n
Dans ce contexte, un effet indésirable d'un médicament est une réaction nocive et non voulue, se produisant aux posologies normalement utilisées chez l'homme pour la prophylaxie, le diagnostic ou le traitement d'une maladie ou la modification d'une fonction physiologique, ou résultant d'un mésusage du médicament.
\n
2. Dans le cas de vaccins déjà autorisés dans d'autres pays, des informations sur le suivi de sujets vaccinés sont fournies lorsque celles-ci sont disponibles afin que soit évaluée la prévalence de l'affection en question, en comparaison avec un groupe de personnes non vaccinées.
\n
3. Pour les produits allergènes, la réaction en période d'exposition accrue à l'antigène doit être décrite.
" } }, "LEGIARTI000006800056": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5117", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1990-09-29", "DATE_DEBUT": "1956-11-28" } }, "META_COMMUN": { "ID": "LEGIARTI000006800056", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800056.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5117R0000XXAA" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "JORFTEXT000000518702", "#text": "Décret 72-1062 1972-11-21 ART. 1 JORF 30 novembre 1972", "@sens": "source", "@cidtexte": "JORFTEXT000000518702", "@numtexte": "72-1062", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-11-21" }, { "@id": "LEGIARTI000006693701", "@num": "L601", "#text": "Code de la santé publique - art. L601 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800067", "@num": "R5119", "#text": "Code de la santé publique - art. R5119 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800076", "@num": "R5120", "#text": "Code de la santé publique - art. R5120 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800082", "@num": "R5121", "#text": "Code de la santé publique - art. R5121 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914724", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914725", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800086", "@num": "R5122", "#text": "Code de la santé publique - art. R5122 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800090", "@num": "R5123", "#text": "Code de la santé publique - art. R5123 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800097", "@num": "R5124", "#text": "Code de la santé publique - art. R5124 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800104", "@num": "R5125", "#text": "Code de la santé publique - art. R5125 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800109", "@num": "R5126", "#text": "Code de la santé publique - art. R5126 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800113", "@num": "R5127", "#text": "Code de la santé publique - art. R5127 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006801404", "@num": "R5229-4", "#text": "Code de la santé publique - art. R5229-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGITEXT000006072665", "#text": "Code de la santé publique L601, L605 AL. 6, R5118, R5119, R5120, R5121, R5122, R5123, R5124, R5125, R5126, R5127", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Décret 60-326 1960-04-05 ART. 10 JORF 7 avril 1960", "@sens": "source", "@typelien": "MODIFICATION" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187146", "@fin": "1994-01-09", "#text": "Paragraphe 1 : Expérimentation des médicaments.", "@debut": "1956-11-28" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800056", "@fin": "1990-09-29", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800057", "@fin": "1994-01-09", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800058", "@fin": "1998-02-13", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800059", "@fin": "2004-08-08", "@num": "R5117", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
L'expérimentation des médicaments, au sens du 6° de l'article L. 605, s'entend des expertises auxquelles il est procédé, dans les conditions fixées aux articles R. 5118 à R. 5127, en vue de vérifier qu'un produit susceptible de faire l'objet d'une demande d'autorisation de mise sur le marché, possède les propriétés définies au 1° du troisième alinéa de l'article L. 601.
\n
" } }, "LEGIARTI000006800057": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5117", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1994-01-09", "DATE_DEBUT": "1990-09-29" } }, "META_COMMUN": { "ID": "LEGIARTI000006800057", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800057.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5117R0000XXAB" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006710227", "@num": "3", "#text": "Décret n°90-872 du 27 septembre 1990 - art. 3 () JORF 29 septembre 1990", "@sens": "source", "@cidtexte": "JORFTEXT000000342246", "@nortexte": "SPSM9001613D", "@numtexte": "90-872", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1990-09-27" }, { "@id": "LEGIARTI000006693742", "@num": "L605", "#text": "Code de la santé publique - art. L605 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800067", "@num": "R5119", "#text": "Code de la santé publique - art. R5119 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800073", "@num": "R5119-1", "#text": "Code de la santé publique - art. R5119-1 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914724", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914725", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006801404", "@num": "R5229-4", "#text": "Code de la santé publique - art. R5229-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187146", "@fin": "1994-01-09", "#text": "Paragraphe 1 : Expérimentation des médicaments.", "@debut": "1956-11-28" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800056", "@fin": "1990-09-29", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800057", "@fin": "1994-01-09", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800058", "@fin": "1998-02-13", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800059", "@fin": "2004-08-08", "@num": "R5117", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
On entend par expérimentation des médicaments, au sens du 6 de l'article L. 605, toutes recherches, essais, ou expérimentations, ci-après dénommés essais, auxquels il est procédé :
\n
1° En vue de l'obtention d'une autorisation de mise sur le marché ;
\n
2° Après la délivrance de cette autorisation.
\n
Sans préjudice des dispositions législatives et réglementaires du livre II bis du présent code, ces essais sont réalisés dans les conditions fixées au présent paragraphe.
" } }, "LEGIARTI000006800058": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5117", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1998-02-13", "DATE_DEBUT": "1994-01-09" } }, "META_COMMUN": { "ID": "LEGIARTI000006800058", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800058.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5117R0000XXAC" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006698601", "@num": "7", "#text": "Décret n°94-19 du 5 janvier 1994 - art. 7 () JORF 9 janvier 1994", "@sens": "source", "@cidtexte": "JORFTEXT000000180444", "@nortexte": "SPSM9303267D", "@numtexte": "94-19", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1994-01-05" }, { "@id": "LEGIARTI000006693742", "@num": "L605", "#text": "Code de la santé publique - art. L605 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800067", "@num": "R5119", "#text": "Code de la santé publique - art. R5119 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800073", "@num": "R5119-1", "#text": "Code de la santé publique - art. R5119-1 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914724", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914725", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006801404", "@num": "R5229-4", "#text": "Code de la santé publique - art. R5229-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187366", "@fin": "1998-02-13", "#text": "Paragraphe 1 : Expérimentation des médicaments", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174540", "@fin": "1998-02-13", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800056", "@fin": "1990-09-29", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800057", "@fin": "1994-01-09", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800058", "@fin": "1998-02-13", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800059", "@fin": "2004-08-08", "@num": "R5117", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
On entend par expérimentation des médicaments, au sens du 6 de l'article L. 605, toutes recherches, essais, ou expérimentations, ci-après dénommés essais, auxquels il est procédé :
\n
1° En vue de l'obtention d'une autorisation de mise sur le marché ;
\n
2° Après la délivrance de cette autorisation.
\n
Sans préjudice des dispositions législatives et réglementaires du livre II bis du présent code, ces essais sont réalisés dans les conditions fixées au présent paragraphe.
" } }, "LEGIARTI000006800059": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5117", "ETAT": "ABROGE", "TYPE": "AUTONOME", "DATE_FIN": "2004-08-08", "DATE_DEBUT": "1998-02-13" } }, "META_COMMUN": { "ID": "LEGIARTI000006800059", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800059.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5117R0000XXAD" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "JORFTEXT000000372654", "#text": "Décret 98-79 1998-02-11 art. 11 : conditions d'application", "@sens": "source", "@cidtexte": "JORFTEXT000000372654", "@nortexte": "MESP9820016D", "@numtexte": "98-79", "@typelien": "SPEC_APPLI", "@naturetexte": "DECRET", "@datesignatexte": "1998-02-11" }, { "@id": "LEGIARTI000006722892", "@num": "6", "#text": "Décret n°98-79 du 11 février 1998 - art. 6 () JORF 13 février 1998", "@sens": "source", "@cidtexte": "JORFTEXT000000372654", "@nortexte": "MESP9820016D", "@numtexte": "98-79", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1998-02-11" }, { "@id": "JORFTEXT000000787339", "#text": "Décret 2004-802 2004-07-29 art. 4 JORF 8 août 2004", "@sens": "source", "@cidtexte": "JORFTEXT000000787339", "@nortexte": "SANP0422530D", "@numtexte": "2004-802", "@typelien": "ABROGATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-29" }, { "@id": "LEGIARTI000006693742", "@num": "L605", "#text": "Code de la santé publique - art. L605 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800067", "@num": "R5119", "#text": "Code de la santé publique - art. R5119 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800073", "@num": "R5119-1", "#text": "Code de la santé publique - art. R5119-1 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914724", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914725", "@num": "R5121-10", "#text": "Code de la santé publique - art. R5121-10 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006801404", "@num": "R5229-4", "#text": "Code de la santé publique - art. R5229-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187436", "@fin": "2004-08-08", "#text": "Paragraphe 1 : Expérimentation des médicaments", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174542", "@fin": "2004-08-08", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157770", "@fin": "2004-08-08", "#text": "Chapitre 2 : Fabrication, exploitation, importation, distribution en gros, exportation des médicaments et autres produits pharmaceutiques à usage humain", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800056", "@fin": "1990-09-29", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800057", "@fin": "1994-01-09", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800058", "@fin": "1998-02-13", "@num": "R5117", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800059", "@fin": "2004-08-08", "@num": "R5117", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
On entend par expérimentation des médicaments , au sens du 6 de l'article L. 605, tous recherches, essais, ou expérimentations, ci-après dénommés essais, auxquels il est procédé :
\n
1° En vue de l'obtention d'une autorisation de mise sur le marché ;
\n
2° Après la délivrance de cette autorisation.
\n
Sans préjudice des dispositions législatives et réglementaires du livre II bis du présent code, ces essais sont réalisés dans les conditions fixées au présent paragraphe.
" } }, "LEGIARTI000006800097": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5124", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1990-09-29", "DATE_DEBUT": "1956-11-28" } }, "META_COMMUN": { "ID": "LEGIARTI000006800097", "URL": "article/LEGI/ARTI/00/00/06/80/00/LEGIARTI000006800097.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5124R0000XXAA" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "JORFTEXT000000518702", "#text": "Décret 72-1062 1972-11-21 ART. 1 JORF 30 novembre 1972", "@sens": "source", "@cidtexte": "JORFTEXT000000518702", "@numtexte": "72-1062", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-11-21" }, { "@id": "JORFTEXT000000307595", "#text": "Décret 78-988 1978-09-20 ART. 1 JORF 6 octobre 1978", "@sens": "source", "@cidtexte": "JORFTEXT000000307595", "@numtexte": "78-988", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1978-09-20" }, { "@id": "LEGIARTI000006800056", "@num": "R5117", "#text": "Code de la santé publique - art. R5117 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914738", "@num": "R5121-17", "#text": "Code de la santé publique - art. R5121-17 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914739", "@num": "R5121-17", "#text": "Code de la santé publique - art. R5121-17 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800108", "@num": "R5125", "#text": "Code de la santé publique - art. R5125 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006801548", "@num": "R5272", "#text": "Code de la santé publique - art. R5272 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Décret 60-326 1960-04-05 ART. 10 JORF 7 avril 1960", "@sens": "source", "@typelien": "MODIFICATION" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187146", "@fin": "1994-01-09", "#text": "Paragraphe 1 : Expérimentation des médicaments.", "@debut": "1956-11-28" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800097", "@fin": "1990-09-29", "@num": "R5124", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800098", "@fin": "1994-01-09", "@num": "R5124", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800099", "@fin": "1998-02-13", "@num": "R5124", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800100", "@fin": "2004-08-08", "@num": "R5124", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Le programme des expertises est déterminé par le responsable de la mise sur le marché et l'expert, compte tenu des règles générales d'expertise définies à la présente section.
\n
\n
Si l'expert justifie que les protocoles prévus à l'article R. 5118 sont inapplicables en l'espèce, le responsable de la mise sur le marché est tenu de communiquer au ministre chargé de la santé publique le programme des expertises retenu préalablement à la mise en oeuvre de celles-ci.
\n
\n
Ce programme peut être mis à exécution si le ministre chargé de la santé publique n'a pas formulé d'opposition dans le délai d'un mois à compter de la réception de la communication ci-dessus indiquée .
\n
" } }, "LEGIARTI000006800105": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5125", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1990-09-29", "DATE_DEBUT": "1988-05-04" } }, "META_COMMUN": { "ID": "LEGIARTI000006800105", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800105.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5125R0000XXAB" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "JORFTEXT000000510098", "#text": "Décret 88-492 1988-05-02 art. 2 JORF 4 mai 1988", "@sens": "source", "@cidtexte": "JORFTEXT000000510098", "@nortexte": "ASEM8800584D", "@numtexte": "88-492", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1988-05-02" }, { "@id": "LEGIARTI000006800042", "@num": "R5115-9", "#text": "Code de la santé publique - art. R5115-9 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800056", "@num": "R5117", "#text": "Code de la santé publique - art. R5117 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914741", "@num": "R5121-19", "#text": "Code de la santé publique - art. R5121-19 (Ab)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914741", "@num": "R5121-19", "#text": "Code de la santé publique - art. R5121-19 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187146", "@fin": "1994-01-09", "#text": "Paragraphe 1 : Expérimentation des médicaments.", "@debut": "1956-11-28" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800104", "@fin": "1988-05-04", "@num": "R5125", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800105", "@fin": "1990-09-29", "@num": "R5125", "@etat": "MODIFIE", "@debut": "1988-05-04", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800106", "@fin": "1994-01-09", "@num": "R5125", "@etat": "MODIFIE", "@debut": "1990-09-29", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800107", "@fin": "1998-02-13", "@num": "R5125", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800108", "@fin": "2004-08-08", "@num": "R5125", "@etat": "ABROGE", "@debut": "1998-02-13", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Les rapports d'expertise doivent mentionner, pour chaque essai :
\n
a) Les nom et prénoms du ou des experts, ainsi que leurs adresses professionnelles, leurs activités professionnelles, leurs fonctions et titres universitaires ;
\n
b) La formule chimique du médicament ainsi que la formule galénique et les changements qui ont pu être apportés à cette dernière formule au cours des expérimentations ;
\n
c) Les dates et lieux de réalisation des expertises ;
\n
d) Le cas échéant, la description détaillée des échecs rencontrés au cours des expérimentations ;
\n
e) En cas de besoin, la conformité aux dispositions des articles R. 5115-9 ou R. 5118.
" } }, "LEGIARTI000006800141": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1988-05-08", "DATE_DEBUT": "1956-11-28" } }, "META_COMMUN": { "ID": "LEGIARTI000006800141", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800141.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAA" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "JORFTEXT000000518702", "#text": "Décret 72-1062 1972-11-21 ART. 1 JORF 30 novembre 1972", "@sens": "source", "@cidtexte": "JORFTEXT000000518702", "@numtexte": "72-1062", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-11-21" }, { "@id": "JORFTEXT000000307595", "#text": "Décret 78-988 1978-09-20 ART. 9 JORF 6 octobre 1978", "@sens": "source", "@cidtexte": "JORFTEXT000000307595", "@numtexte": "78-988", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1978-09-20" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Décret 60-326 1960-04-05 ART. 10 JORF 7 avril 1960", "@sens": "source", "@typelien": "MODIFICATION" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187147", "@fin": "1994-01-09", "#text": "PARAGRAPHE 2 : AUTORISATION DE MISE SUR LE MARCHE.", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le ministre chargé de la santé peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
c) Une documentation bibliographique peut tenir lieu de comptes rendus des essais pharmacologiques, toxicologiques et cliniques lorsqu'il s'agit :
\n
D'une spécialité déjà exploitée ayant été expérimentée d'une manière suffisante sur l'homme pour que ses effets, y compris les effets secondaires, soient déjà connus et figurent dans la documentation bibliographique ;
\n
D'une spécialité nouvelle dont la composition en principes actifs est identique à celle d'une spécialité déjà connue et exploitée ;
\n
D'une spécialité nouvelle renfermant uniquement des composants connus, déjà associés en proportion comparable dans des médicaments et suffisamment expérimentés et déjà exploités.
\n
Dans ces trois cas, les experts doivent justifier le recours à la documentation bibliographique et démontrer que la bibliographie satisfait aux exigences de protocoles arrêtés par application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus qui n'ont pas encore été associés dans un but thérapeutique, les essais concernant ces composants peuvent être remplacés par la présentation d'une documentation bibliographique.
\n
" } }, "LEGIARTI000006800142": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1993-08-07", "DATE_DEBUT": "1988-05-08" } }, "META_COMMUN": { "ID": "LEGIARTI000006800142", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800142.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAB" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "JORFTEXT000000312908", "#text": "Décret 88-661 1988-05-06 art. 3 JORF 8 mai 1988", "@sens": "source", "@cidtexte": "JORFTEXT000000312908", "@nortexte": "ASEM8800585D", "@numtexte": "88-661", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1988-05-06" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187147", "@fin": "1994-01-09", "#text": "PARAGRAPHE 2 : AUTORISATION DE MISE SUR LE MARCHE.", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le ministre chargé de la santé peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
\n
c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
\n
1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
\n
2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
\n
3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
\n
Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel.
\n
Lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
" } }, "LEGIARTI000006800143": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1994-01-09", "DATE_DEBUT": "1993-08-07" } }, "META_COMMUN": { "ID": "LEGIARTI000006800143", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800143.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAC" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "LEGIARTI000006713445", "@num": "7", "#text": "Décret n°93-982 du 5 août 1993 - art. 7 () JORF 7 août 1993", "@sens": "source", "@cidtexte": "JORFTEXT000000727412", "@nortexte": "SPSP9302069D", "@numtexte": "93-982", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-08-05" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187147", "@fin": "1994-01-09", "#text": "PARAGRAPHE 2 : AUTORISATION DE MISE SUR LE MARCHE.", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174539", "@fin": "1994-01-09", "#text": "Section 2 : Spécialités pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le directeur général de l'Agence du médicament peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
\n
c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
\n
1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
\n
2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
\n
3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
\n
Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel.
\n
Lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
" } }, "LEGIARTI000006800144": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1998-01-30", "DATE_DEBUT": "1994-01-09" } }, "META_COMMUN": { "ID": "LEGIARTI000006800144", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800144.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAD" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006698601", "@num": "7", "#text": "Décret n°94-19 du 5 janvier 1994 - art. 7 () JORF 9 janvier 1994", "@sens": "source", "@cidtexte": "JORFTEXT000000180444", "@nortexte": "SPSM9303267D", "@numtexte": "94-19", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1994-01-05" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187149", "@fin": "1998-02-13", "#text": "Paragraphe 2 : Autorisation de mise sur le marché", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174540", "@fin": "1998-02-13", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le directeur général de l'Agence du médicament peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
\n
c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
\n
1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
\n
2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
\n
3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
\n
Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel.
\n
Lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
" } }, "LEGIARTI000006800145": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1998-02-13", "DATE_DEBUT": "1998-01-30" } }, "META_COMMUN": { "ID": "LEGIARTI000006800145", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800145.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAE" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "LEGIARTI000006722860", "@num": "2", "#text": "Décret n°98-52 du 28 janvier 1998 - art. 2 () JORF 30 janvier 1998", "@sens": "source", "@cidtexte": "JORFTEXT000000387206", "@nortexte": "MESP9723639D", "@numtexte": "98-52", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1998-01-28" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187149", "@fin": "1998-02-13", "#text": "Paragraphe 2 : Autorisation de mise sur le marché", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174540", "@fin": "1998-02-13", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1994-01-09" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157765", "@fin": "1998-02-13", "#text": "Chapitre 2 : Préparation et vente en gros des produits pharmaceutiques", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
I. - Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le directeur général de l'Agence du médicament peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
\n
c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
\n
1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
\n
2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
\n
3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
\n
Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel.
\n
\n
e) Pour un médicament homéopathique soumis à autorisation de mise sur le marché, compte tenu de la spécificité de ce médicament, le demandeur est dispensé de produire tout ou partie des résultats des essais pharmacologiques, toxicologiques et cliniques lorsqu'il peut démontrer par référence détaillée à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France que l'usage homéopathique du médicament ou des souches homéopathiques le composant est bien établi et présente toutes garanties d'innocuité.
\n
\n
II. - 1. Pour l'application du c du I, lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
\n
2. Pour l'application du e du I, lorsqu'il est fait référence à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France, des experts doivent justifier, sur la base de la documentation fournie :
\n
a) Le caractère homéopathique des souches utilisées et leur utilisation traditionnelle dans l'indication revendiquée ;
\n
b) L'innocuité du médicament homéopathique, notamment au regard du degré de dilution de chacun de ses composants ;
\n
c) La voie d'administration, pour les médicaments homéopathiques injectables.
" } }, "LEGIARTI000006800146": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "1999-03-05", "DATE_DEBUT": "1998-02-13" } }, "META_COMMUN": { "ID": "LEGIARTI000006800146", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800146.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAF" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "JORFTEXT000000372654", "#text": "Décret 98-79 1998-02-11 art. 11 : conditions d'application", "@sens": "source", "@cidtexte": "JORFTEXT000000372654", "@nortexte": "MESP9820016D", "@numtexte": "98-79", "@typelien": "SPEC_APPLI", "@naturetexte": "DECRET", "@datesignatexte": "1998-02-11" }, { "@id": "LEGIARTI000006722892", "@num": "6", "#text": "Décret n°98-79 du 11 février 1998 - art. 6 () JORF 13 février 1998", "@sens": "source", "@cidtexte": "JORFTEXT000000372654", "@nortexte": "MESP9820016D", "@numtexte": "98-79", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1998-02-11" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187164", "@fin": "2004-08-08", "#text": "Paragraphe 2 : Autorisation de mise sur le marché", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174542", "@fin": "2004-08-08", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157770", "@fin": "2004-08-08", "#text": "Chapitre 2 : Fabrication, exploitation, importation, distribution en gros, exportation des médicaments et autres produits pharmaceutiques à usage humain", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
I. - Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
\n
\n
a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le directeur général de l'Agence du médicament peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
\n
\n
b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
\n
\n
c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
\n
1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
\n
2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
\n
3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
\n
Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
\n
d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel ;
\n
\n
e) Pour un médicament homéopathique soumis à autorisation de mise sur le marché, compte tenu de la spécificité de ce médicament, le demandeur est dispensé de produire tout ou partie des résultats des essais pharmacologiques, toxicologiques et cliniques lorsqu'il peut démontrer par référence détaillée à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France que l'usage homéopathique du médicament ou des souches homéopathiques le composant est bien établi et présente toutes garanties d'innocuité.
\n
\n
II. - 1. Pour l'application du c du I, lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
\n
2. Pour l'application du e du I, lorsqu'il est fait référence à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France, des experts doivent justifier, sur la base de la documentation fournie :
\n
a) Le caractère homéopathique des souches utilisées et leur utilisation traditionnelle dans l'indication revendiquée ;
\n
b) L'innocuité du médicament homéopathique, notamment au regard du degré de dilution de chacun de ses composants ;
\n
c) La voie d'administration, pour les médicaments homéopathiques injectables.
" } }, "LEGIARTI000006800147": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5133", "ETAT": "ABROGE", "TYPE": "AUTONOME", "DATE_FIN": "2004-08-08", "DATE_DEBUT": "1999-03-05" } }, "META_COMMUN": { "ID": "LEGIARTI000006800147", "URL": "article/LEGI/ARTI/00/00/06/80/01/LEGIARTI000006800147.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "SXXXXXXXXXX5133R0000XXAG" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000503843", "#text": "Décret 53-1001 1953-10-05 (Décret de codification)", "@sens": "source", "@cidtexte": "JORFTEXT000000503843", "@numtexte": "53-1001", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1953-10-05" }, { "@id": "LEGIARTI000006701352", "@num": "2", "#text": "Décret n°72-642 du 3 juillet 1972 - art. 2 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000858492", "@numtexte": "72-642", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1972-07-03" }, { "@id": "LEGIARTI000006713571", "@num": "1", "#text": "Décret n°93-1322 du 20 décembre 1993 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000518210", "@nortexte": "SPSM9302869D", "@numtexte": "93-1322", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1993-12-20" }, { "@id": "LEGIARTI000006700475", "@num": "1", "#text": "Décret n°96-653 du 16 juillet 1996 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000548104", "@nortexte": "TASM9620899D", "@numtexte": "96-653", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1996-07-16" }, { "@id": "LEGIARTI000006732698", "@num": "ANNEXE", "#text": "Arrêté du 9 décembre 1996 - art. ANNEXE (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000747887", "@nortexte": "TASP9624370A", "@typelien": "CITATION", "@naturetexte": "ARRETE", "@datesignatexte": "1996-12-09" }, { "@id": "JORFTEXT000000372654", "#text": "Décret 98-79 1998-02-11 art. 11 : conditions d'application", "@sens": "source", "@cidtexte": "JORFTEXT000000372654", "@nortexte": "MESP9820016D", "@numtexte": "98-79", "@typelien": "SPEC_APPLI", "@naturetexte": "DECRET", "@datesignatexte": "1998-02-11" }, { "@id": "LEGIARTI000006723508", "@num": "1", "#text": "Décret n°99-144 du 4 mars 1999 - art. 1 () JORF 5 mars 1999", "@sens": "source", "@cidtexte": "JORFTEXT000000758693", "@nortexte": "MESP9824093D", "@numtexte": "99-144", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-03-04" }, { "@id": "LEGIARTI000006723667", "@num": "8", "#text": "Décret n°99-486 du 11 juin 1999 - art. 8 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000760344", "@nortexte": "MESP9921746D", "@numtexte": "99-486", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "1999-06-11" }, { "@id": "LEGIARTI000006232079", "@num": "1", "#text": "Décret n°2004-651 du 2 juillet 2004 - art. 1 (Ab)", "@sens": "cible", "@cidtexte": "JORFTEXT000000436350", "@nortexte": "SANG0421846D", "@numtexte": "2004-651", "@typelien": "CITATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-02" }, { "@id": "JORFTEXT000000787339", "#text": "Décret 2004-802 2004-07-29 art. 4 JORF 8 août 2004", "@sens": "source", "@cidtexte": "JORFTEXT000000787339", "@nortexte": "SANP0422530D", "@numtexte": "2004-802", "@typelien": "ABROGATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-29" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914752", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914754", "@num": "R5121-29", "#text": "Code de la santé publique - art. R5121-29 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914755", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914756", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914757", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006914758", "@num": "R5121-31", "#text": "Code de la santé publique - art. R5121-31 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800117", "@num": "R5128", "#text": "Code de la santé publique - art. R5128 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800126", "@num": "R5129", "#text": "Code de la santé publique - art. R5129 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800176", "@num": "R5136", "#text": "Code de la santé publique - art. R5136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800272", "@num": "R5143", "#text": "Code de la santé publique - art. R5143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "#text": "Loi 58-356 1958-04-03 (Loi de validation)", "@sens": "source", "@typelien": "CODIFICATION" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006187164", "@fin": "2004-08-08", "#text": "Paragraphe 2 : Autorisation de mise sur le marché", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006174542", "@fin": "2004-08-08", "#text": "Section 2 : Médicaments et produits soumis à autorisation", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006157770", "@fin": "2004-08-08", "#text": "Chapitre 2 : Fabrication, exploitation, importation, distribution en gros, exportation des médicaments et autres produits pharmaceutiques à usage humain", "@debut": "1998-02-13" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006142899", "@fin": "2999-01-01", "#text": "Titre 2 : Dispositions particulières aux divers modes d'exercice de la pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006128471", "@fin": "2999-01-01", "#text": "Livre 5 : Pharmacie", "@debut": "1953-10-07" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006107982", "@fin": "2999-01-01", "#text": "Partie réglementaire ancienne", "@debut": "1953-10-07" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800141", "@fin": "1988-05-08", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1956-11-28", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800142", "@fin": "1993-08-07", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1988-05-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800143", "@fin": "1994-01-09", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1993-08-07", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800144", "@fin": "1998-01-30", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1994-01-09", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800145", "@fin": "1998-02-13", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-01-30", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006800146", "@fin": "1999-03-05", "@num": "R5133", "@etat": "MODIFIE", "@debut": "1998-02-13", "@origine": "LEGI" } }, { "@etat": "ABROGE", "LIEN_ART": { "@id": "LEGIARTI000006800147", "@fin": "2004-08-08", "@num": "R5133", "@etat": "ABROGE", "@debut": "1999-03-05", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
I. - Par dérogation aux dispositions des articles R. 5128 et R. 5129 :
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a) Lorsque la demande porte sur une modification d'autorisation de mise sur le marché, le directeur général de l'Agence française de sécurité sanitaire des produits de santé peut dispenser le demandeur de produire certaines des indications ou justifications exigées par les articles R. 5128 et R. 5129 s'il apparaît que celles-ci sont manifestement sans objet ;
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b) Lorsque la demande concerne une spécialité correspondant à une préparation figurant à la Pharmacopée française ou au formulaire national, le demandeur peut être dispensé des expertises pharmacologiques, toxicologiques et cliniques ;
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c) Le demandeur n'est pas tenu de fournir les résultats des essais pharmacologiques et toxicologiques ni les résultats des essais cliniques s'il peut démontrer :
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1. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée et que la personne responsable de la mise sur le marché de la spécialité originale a consenti qu'il soit fait recours en vue de l'examen de la présente demande à la documentation pharmacologique, toxicologique ou clinique figurant au dossier de la spécialité originale ;
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2. Soit, par référence détaillée à la littérature scientifique publiée, que le ou les composants de la spécialité pharmaceutique sont d'un usage médical bien établi et présentent une efficacité reconnue, ainsi qu'un niveau acceptable de sécurité ;
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3. Soit que la spécialité pharmaceutique est essentiellement similaire à une spécialité autorisée depuis au moins dix ans en France ou dans un autre pays membre des communautés européennes selon les dispositions communautaires en vigueur et commercialisée en France.
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Cependant, dans le cas où la spécialité pharmaceutique est destinée à un usage thérapeutique différent ou doit être administrée par des voies différentes ou sous un dosage différent, par rapport aux autres médicaments commercialisés, les résultats des essais pharmacologiques, toxicologiques et cliniques appropriés doivent être fournis.
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d) En ce qui concerne une spécialité nouvelle renfermant des composants connus, mais qui n'ont pas encore été associés dans un but thérapeutique, les résultats des essais pharmacologiques, toxicologiques et cliniques relatifs à l'association doivent être fournis sans qu'il soit nécessaire de fournir la documentation relative à chaque composant individuel ;
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e) Pour un médicament homéopathique soumis à autorisation de mise sur le marché, compte tenu de la spécificité de ce médicament, le demandeur est dispensé de produire tout ou partie des résultats des essais pharmacologiques, toxicologiques et cliniques lorsqu'il peut démontrer par référence détaillée à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France que l'usage homéopathique du médicament ou des souches homéopathiques le composant est bien établi et présente toutes garanties d'innocuité.
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II. - 1. Pour l'application du c du I, lorsqu'il est fait référence à la littérature scientifique publiée, des experts doivent justifier le recours à cette documentation bibliographique et démontrer qu'elle satisfait aux exigences des protocoles arrêtés en application de l'article R. 5118, compte tenu notamment de la forme pharmaceutique et des constituants de l'excipient.
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2. Pour l'application du e du I, lorsqu'il est fait référence à la littérature publiée et reconnue dans la tradition de la médecine homéopathique pratiquée en France, des experts doivent justifier, sur la base de la documentation fournie :
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a) Le caractère homéopathique des souches utilisées et leur utilisation traditionnelle dans l'indication revendiquée ;
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b) L'innocuité du médicament homéopathique, notamment au regard du degré de dilution de chacun de ses composants ;
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c) La voie d'administration, pour les médicaments homéopathiques injectables.
" } }, "LEGIARTI000006914726": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5121-11", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "2006-04-27", "DATE_DEBUT": "2004-08-08" } }, "META_COMMUN": { "ID": "LEGIARTI000006914726", "URL": "article/LEGI/ARTI/00/00/06/91/47/LEGIARTI000006914726.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "YXXXXXXXXXX5121R0110XX0A" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000787339", "#text": "Décret 2004-802 2004-07-29", "@sens": "source", "@cidtexte": "JORFTEXT000000787339", "@nortexte": "SANP0422530D", "@numtexte": "2004-802", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-29" }, { "@id": "LEGIARTI000006800066", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000018776582", "@num": "R5121-107-4", "#text": "Code de la santé publique - art. R5121-107-4 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000026903038", "@num": "R5121-25", "#text": "Code de la santé publique - art. R5121-25 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000018776221", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000037269752", "@num": "R5521-1", "#text": "Code de la santé publique - art. R5521-1 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006190664", "@fin": "2999-01-01", "#text": "Section 4 : Expérimentations", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006178649", "@fin": "2999-01-01", "#text": "Chapitre Ier : Dispositions générales", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006161012", "@fin": "2999-01-01", "#text": "Titre II : Médicaments à usage humain", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006145489", "@fin": "2999-01-01", "#text": "Livre Ier : Produits pharmaceutiques", "@debut": "2004-07-29" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006132399", "@fin": "2999-01-01", "#text": "Cinquième partie : Produits de santé", "@debut": "2004-07-29" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006112927", "@fin": "2999-01-01", "#text": "Partie réglementaire", "@debut": "2000-12-23" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006914726", "@fin": "2006-04-27", "@num": "R5121-11", "@etat": "MODIFIE", "@debut": "2004-08-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006914727", "@fin": "2012-05-01", "@num": "R5121-11", "@etat": "MODIFIE", "@debut": "2006-04-27", "@origine": "LEGI" } }, { "@etat": "VIGUEUR", "LIEN_ART": { "@id": "LEGIARTI000025788183", "@fin": "2999-01-01", "@num": "R5121-11", "@etat": "VIGUEUR", "@debut": "2012-05-01", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Les normes et méthodes applicables à l'expérimentation des médicaments sont fixées, sur proposition du directeur général de l'Agence française de sécurité sanitaire des produits de santé, par arrêté du ministre chargé de la santé.
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Les essais sont réalisés en conformité avec les bonnes pratiques de laboratoire et les bonnes pratiques cliniques dont les principes sont fixés, sur proposition du directeur général de l'Agence française de sécurité sanitaire des produits de santé, par arrêté du ministre chargé de la santé.
" } }, "LEGIARTI000006914727": { "META": { "META_SPEC": { "META_ARTICLE": { "NUM": "R5121-11", "ETAT": "MODIFIE", "TYPE": "AUTONOME", "DATE_FIN": "2012-05-01", "DATE_DEBUT": "2006-04-27" } }, "META_COMMUN": { "ID": "LEGIARTI000006914727", "URL": "article/LEGI/ARTI/00/00/06/91/47/LEGIARTI000006914727.xml", "NATURE": "Article", "ORIGINE": "LEGI", "ANCIEN_ID": "YXXXXXXXXXX5121R0110XX0B" } }, "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000787339", "#text": "Décret 2004-802 2004-07-29", "@sens": "source", "@cidtexte": "JORFTEXT000000787339", "@nortexte": "SANP0422530D", "@numtexte": "2004-802", "@typelien": "CODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "2004-07-29" }, { "@id": "LEGIARTI000006250974", "@num": "5", "#text": "Décret n°2006-477 du 26 avril 2006 - art. 5 () JORF 27 avril 2006", "@sens": "source", "@cidtexte": "JORFTEXT000000458901", "@nortexte": "SANP0524369D", "@numtexte": "2006-477", "@typelien": "MODIFICATION", "@naturetexte": "DECRET", "@datesignatexte": "2006-04-26" }, { "@id": "LEGIARTI000006800066", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "source", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CONCORDANCE", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000018776582", "@num": "R5121-107-4", "#text": "Code de la santé publique - art. R5121-107-4 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000026903038", "@num": "R5121-25", "#text": "Code de la santé publique - art. R5121-25 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000018776221", "@num": "R5121-30", "#text": "Code de la santé publique - art. R5121-30 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000037269752", "@num": "R5521-1", "#text": "Code de la santé publique - art. R5521-1 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CITATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" } ] }, "CONTEXTE": { "TEXTE": { "TM": { "TM": { "TM": { "TM": { "TM": { "TM": { "TITRE_TM": [ { "@id": "LEGISCTA000006190664", "@fin": "2999-01-01", "#text": "Section 4 : Expérimentations", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006178649", "@fin": "2999-01-01", "#text": "Chapitre Ier : Dispositions générales", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006161012", "@fin": "2999-01-01", "#text": "Titre II : Médicaments à usage humain", "@debut": "2004-08-08" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006145489", "@fin": "2999-01-01", "#text": "Livre Ier : Produits pharmaceutiques", "@debut": "2004-07-29" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006132399", "@fin": "2999-01-01", "#text": "Cinquième partie : Produits de santé", "@debut": "2004-07-29" } ] }, "TITRE_TM": [ { "@id": "LEGISCTA000006112927", "@fin": "2999-01-01", "#text": "Partie réglementaire", "@debut": "2000-12-23" } ] }, "@cid": "LEGITEXT000006072665", "@nature": "CODE", "TITRE_TXT": [ { "@fin": "2999-01-01", "#text": "Code de la santé publique", "@debut": "1953-10-07", "@id_txt": "LEGITEXT000006072665", "@c_titre_court": "Code de la santé publique" } ], "@date_publi": "2999-01-01", "@date_signature": "2999-01-01" } }, "VERSIONS": { "VERSION": [ { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006914726", "@fin": "2006-04-27", "@num": "R5121-11", "@etat": "MODIFIE", "@debut": "2004-08-08", "@origine": "LEGI" } }, { "@etat": "MODIFIE", "LIEN_ART": { "@id": "LEGIARTI000006914727", "@fin": "2012-05-01", "@num": "R5121-11", "@etat": "MODIFIE", "@debut": "2006-04-27", "@origine": "LEGI" } }, { "@etat": "VIGUEUR", "LIEN_ART": { "@id": "LEGIARTI000025788183", "@fin": "2999-01-01", "@num": "R5121-11", "@etat": "VIGUEUR", "@debut": "2012-05-01", "@origine": "LEGI" } } ] }, "BLOC_TEXTUEL": { "CONTENU": "
Les normes et méthodes applicables à l'expérimentation des médicaments sont fixées, sur proposition du directeur général de l'Agence française de sécurité sanitaire des produits de santé, par arrêté du ministre chargé de la santé.
\n
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Les normes et méthodes applicables à l'expérimentation des médicaments sont fixées, sur proposition du directeur général de l'Agence nationale de sécurité du médicament et des produits de santé, par arrêté du ministre chargé de la santé.

" } } }, "article_lien": [ { "article_id": "LEGIARTI000006800105", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800056", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006914726", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CONCORDANCE" }, { "article_id": "LEGIARTI000006914727", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CONCORDANCE" }, { "article_id": "LEGIARTI000025788183", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CONCORDANCE" }, { "article_id": "LEGIARTI000006800059", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800057", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800058", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800097", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800141", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800142", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800143", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800144", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800145", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800146", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006800147", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006732698", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" }, { "article_id": "LEGIARTI000006718724", "cible": false, "cidtexte": "LEGITEXT000006072665", "id": "LEGIARTI000006800060", "typelien": "CITATION" } ], "texte_version": { "JORFTEXT000000337674": { "SM": { "CONTENU": "ART: R5118 : LE MINISTRE CHARGE DE LA SANTE FIXE PAR ARRETE LES PROTOCOLES DETERMINANT LES NORMES ET METHODES APPLICABLES A L'EXPERIMENTATION DES MEDICAMENTS (SUPPRESSION DE LA COMMISSION CHARGEE DE PROPOSER LES EXPERTS).
ART. R5119 : QUALIFICATIONS TECHNIQUES ET PROFESSIONNELLES DES CANDIDATS AUX FONCTIONS D'EXPERTS (EXPERTS PHARMACEUTIQUES,EXPERTS TOXICOLOGUES,EXPERTS PHARMACOLOGUES,EXPERTS CLINICIENS).
MODALITES D'ATTRIBUTION DE L'AGREMENT PREVU A L'ART. L605 (2EMEMENT) DU CODE PRECITE." }, "META": { "META_SPEC": { "META_TEXTE_VERSION": { "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000705819", "#text": "Directive 86/609/CEE du Conseil du 24 novembre 1986", "@sens": "source", "@cidtexte": "JORFTEXT000000705819", "@nortexte": "386L0609", "@numtexte": "86-609", "@typelien": "APPLICATION", "@naturetexte": "DIRECTIVE_EURO", "@datesignatexte": "1986-11-24" }, { "@id": "LEGIARTI000006800060", "@num": "R5118", "#text": "Code de la santé publique - art. R5118 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "MODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006800067", "@num": "R5119", "#text": "Code de la santé publique - art. R5119 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "MODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" } ] }, "TITRE": "Décret n°79-256 du 21 mars 1979", "MCS_TXT": { "MC": [ "SANTE PUBLIQUE", "CODE DE LA SANTE PUBLIQUE", "INDUSTRIE PHARMACEUTIQUE", "PRODUIT PHARMACEUTIQUE", "MEDICAMENT", "EXPERIMENTATION", "EXPERT", "NORME", "LABORATOIRE", "EXPERTISE", "AGREMENT", "COMPETENCE", "ESSAI PHARMACEUTIQUE", "ESSAI TOXICOLOGIQUE", "TRANSPOSITION DE DIRECTIVE CE" ] }, "TITREFULL": "Décret n°79-256 du 21 mars 1979 REMPLACANT LES ART. R5118 ET R5119 DU CODE DE LA SANTE PUBLIQUE" }, "META_TEXTE_CHRONICLE": { "CID": "JORFTEXT000000337674", "NUM": "79-256", "DATE_PUBLI": "1979-03-31", "DATE_TEXTE": "1979-03-21", "ORIGINE_PUBLI": "JORF du 31 mars 1979", "PAGE_DEB_PUBLI": 709, "PAGE_FIN_PUBLI": 744 } }, "META_COMMUN": { "ID": "JORFTEXT000000337674", "URL": "texte/version/JORF/TEXT/00/00/00/33/76/JORFTEXT000000337674.xml", "NATURE": "DECRET", "ORIGINE": "JORF", "ANCIEN_ID": "1DX979256" } }, "ENTREPRISE": { "@texte_entreprise": "non" } }, "JORFTEXT000000503843": { "SM": { "CONTENU": "Application de la loi n° 51-518 du 8 mai 1951.‎ Publication en annexe au code de la santé publique, ‎\n‎1) des conventions internationales énumérées à ‎l'article final (792) dudit code (pages 8902 à 8923):‎\n‎-‎ convention franco-luxembourgeoise sur l'exercice de la médecine signée à Paris le 30-09-1879 ;‎\n‎-‎ convention franco-suisse sur l'exercice de la médecine et de l'art vétérinaire signée à Paris le ‎‎29-05-‎‎‎1889 ;‎\n‎-‎ convention franco-belge sur l'exercice de la médecine signée à Bruxelles le 25-10-1910 ;‎\n‎-‎ convention internationale de l'opium signée à la Haye le 23-01-1912 ; protocoles signés à la ‎Haye ‎les ‎‎09-07-1913 et 25-06-1914 ; accords protocoles et actes signés à Genève les 11 et 19-‎‎02-1925, ‎amendés ‎à Lake Success le 11-12-1946 ; protocole signé à Genève le 13-07-1931, ‎amendé à Lake ‎Success le 11-‎‎12-1946 ; accord et acte final signés à Bangkok le 27-11-1931 ; ‎convention protocole et ‎accord signes à ‎Genève le 26-06-1936, amendé à Lake Success le 11-‎‎12-1946 ; protocole signé à Lake ‎Success le 11-12-‎‎1946 ; protocole signé à Paris le 19-11-1948 ;‎\n‎-‎ convention franco-monégasque sur l'exercice de la médecine signée à Paris le 14-12-1938 ;‎\n‎-‎ convention franco-sarroise sur l'exercice de la pharmacie signée à Paris le 03-03-1950 ;‎\n‎-‎ accord franco-sarrois sur l'exercice de la médecine signe à Sarrebruck le 01-12-1951.‎\n‎2) des tables de concordance du code (pages 8924 à 8934).‎\nAux termes de l’article 1er de la loi n° 58-346 du 3 avril 1958, les textes législatifs annexés à ‎cette loi ‎au ‎titre du code de la santé publique‎‎ sont abrogés et remplacés par ledit code. Pour ‎le ‎territoire ‎métropolitain, les dispositions contenues dans le code de la santé publique ont force ‎de ‎loi ‎à compter ‎du 05-04-1958‎‎" }, "ABRO": { "CONTENU": "Texte totalement abrogé sauf l'article 5 et incorporé au code de la santé publique" }, "META": { "META_SPEC": { "META_TEXTE_VERSION": { "LIENS": { "LIEN": [ { "@id": "JORFTEXT000000683983", "#text": "Loi du 31 juillet 1920, v. init.", "@sens": "cible", "@cidtexte": "JORFTEXT000000683983", "@typelien": "MODIFICATION", "@naturetexte": "LOI", "@datesignatexte": "1920-07-31" }, { "@id": "JORFTEXT000000517339", "#text": "Loi n°51-518 du 8 mai 1951", "@sens": "source", "@cidtexte": "JORFTEXT000000517339", "@numtexte": "51-518", "@typelien": "APPLICATION", "@naturetexte": "LOI", "@datesignatexte": "1951-05-08" }, { "@id": "JORFTEXT000000672646", "#text": "Décret n°51-1322 du 6 novembre 1951", "@sens": "source", "@cidtexte": "JORFTEXT000000672646", "@numtexte": "51-1322", "@typelien": "ABROGE", "@naturetexte": "DECRET", "@datesignatexte": "1951-11-06" }, { "@id": "JORFTEXT000000327101", "#text": "Décret n°52-1068 du 25 août 1952", "@sens": "source", "@cidtexte": "JORFTEXT000000327101", "@numtexte": "52-1068", "@typelien": "ABROGE", "@naturetexte": "DECRET", "@datesignatexte": "1952-08-25" }, { "@id": "JORFTEXT000038385399", "#text": "Décret n° 55-512 du 11 mai 1955, v. init.", "@sens": "cible", "@cidtexte": "JORFTEXT000038385399", "@numtexte": "55-512", "@typelien": "MODIFIE", "@naturetexte": "DECRET", "@datesignatexte": "1955-05-11" }, { "@id": "JORFTEXT000029800929", "#text": "Décret n° 56-907 du 10 septembre 1966‎, v. init.", "@sens": "cible", "@cidtexte": "JORFTEXT000029800929", "@numtexte": "56-907", "@typelien": "MODIFIE", "@naturetexte": "DECRET", "@datesignatexte": "1956-09-10" }, { "@id": "JORFTEXT000000874433", "#text": "Loi n°58-91 du 4 février 1958, v. init.", "@sens": "cible", "@cidtexte": "JORFTEXT000000874433", "@numtexte": "58-91", "@typelien": "MODIFIE", "@naturetexte": "LOI", "@datesignatexte": "1958-02-04" }, { "@id": "JORFTEXT000000217229", "#text": "Ordonnance2000-548", "@sens": "cible", "@cidtexte": "JORFTEXT000000217229", "@nortexte": "MESX0000036P", "@typelien": "ABROGE", "@naturetexte": "RAPPORT", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006698233", "@num": "4", "#text": "Rapport - art. 4 (M)", "@sens": "cible", "@cidtexte": "JORFTEXT000000400219", "@nortexte": "MESX0000036R", "@numtexte": "2000-548", "@typelien": "CITATION", "@naturetexte": "ORDONNANCE", "@datesignatexte": "2000-06-15" }, { "@id": "LEGIARTI000006698234", "@num": "4", "#text": "Rapport - art. 4 (V)", "@sens": "cible", "@cidtexte": "JORFTEXT000000400219", "@nortexte": "MESX0000036R", "@numtexte": "2000-548", "@typelien": "CITATION", "@naturetexte": "ORDONNANCE", "@datesignatexte": "2000-06-15" }, { "@id": "LEGIARTI000006804474", "@num": "Annexe V aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. 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Annexe IAb aux articles R665-1 à R665-47 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804465", "@num": "Annexe II aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe II aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804464", "@num": "Annexe II aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe II aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804463", "@num": "Annexe II aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe II aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804492", "@num": "Annexe II aux articles R668-1-1 à R668-21", "#text": "Code de la santé publique - art. Annexe II aux articles R668-1-1 à R668-21 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804468", "@num": "Annexe III aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe III aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804467", "@num": "Annexe III aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe III aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804466", "@num": "Annexe III aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe III aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804470", "@num": "Annexe IV aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IV aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804469", "@num": "Annexe IV aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IV aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804484", "@num": "Annexe IX aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IX aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804483", "@num": "Annexe IX aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IX aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804481", "@num": "Annexe IX aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IX aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804482", "@num": "Annexe IX aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe IX aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804472", "@num": "Annexe V aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe V aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804473", "@num": "Annexe V aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe V aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804475", "@num": "Annexe VI aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe VI aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804477", "@num": "Annexe VII aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe VII aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804479", "@num": "Annexe VIII aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe VIII aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804486", "@num": "Annexe X aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe X aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804485", "@num": "Annexe X aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe X aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804488", "@num": "Annexe XI aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe XI aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804487", "@num": "Annexe XI aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe XI aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804490", "@num": "Annexe XII aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe XII aux articles R665-1 à R665-47 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804489", "@num": "Annexe XII aux articles R665-1 à R665-47", "#text": "Code de la santé publique - art. Annexe XII aux articles R665-1 à R665-47 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006804493", "@num": "Annexe aux articles R710-17-1 à R710-17-9", "#text": "Code de la santé publique - art. Annexe aux articles R710-17-1 à R710-17-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691647", "@num": "D11-1", "#text": "Code de la santé publique - art. D11-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691644", "@num": "D11-1", "#text": "Code de la santé publique - art. D11-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691646", "@num": "D11-1", "#text": "Code de la santé publique - art. D11-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691645", "@num": "D11-1", "#text": "Code de la santé publique - art. D11-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691651", "@num": "D11-2", "#text": "Code de la santé publique - art. D11-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691649", "@num": "D11-2", "#text": "Code de la santé publique - art. D11-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691648", "@num": "D11-2", "#text": "Code de la santé publique - art. D11-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691650", "@num": "D11-2", "#text": "Code de la santé publique - art. D11-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006685740", "@num": "D2001", "#text": "Code de la santé publique - art. D2001 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691652", "@num": "D355-23", "#text": "Code de la santé publique - art. D355-23 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691653", "@num": "D355-23-1", "#text": "Code de la santé publique - art. D355-23-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691654", "@num": "D355-23-2", "#text": "Code de la santé publique - art. D355-23-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691655", "@num": "D355-23-3", "#text": "Code de la santé publique - art. D355-23-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691656", "@num": "D355-23-4", "#text": "Code de la santé publique - art. D355-23-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691657", "@num": "D355-23-5", "#text": "Code de la santé publique - art. D355-23-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691658", "@num": "D665-5-1", "#text": "Code de la santé publique - art. D665-5-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691667", "@num": "D665-5-10", "#text": "Code de la santé publique - art. D665-5-10 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691668", "@num": "D665-5-11", "#text": "Code de la santé publique - art. D665-5-11 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691669", "@num": "D665-5-12", "#text": "Code de la santé publique - art. D665-5-12 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691659", "@num": "D665-5-2", "#text": "Code de la santé publique - art. D665-5-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691660", "@num": "D665-5-3", "#text": "Code de la santé publique - art. D665-5-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691661", "@num": "D665-5-4", "#text": "Code de la santé publique - art. D665-5-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691662", "@num": "D665-5-5", "#text": "Code de la santé publique - art. D665-5-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691663", "@num": "D665-5-6", "#text": "Code de la santé publique - art. D665-5-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691664", "@num": "D665-5-7", "#text": "Code de la santé publique - art. D665-5-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691665", "@num": "D665-5-8", "#text": "Code de la santé publique - art. D665-5-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691666", "@num": "D665-5-9", "#text": "Code de la santé publique - art. D665-5-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691671", "@num": "D666-3-1", "#text": "Code de la santé publique - art. D666-3-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691670", "@num": "D666-3-1", "#text": "Code de la santé publique - art. D666-3-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691673", "@num": "D666-3-2", "#text": "Code de la santé publique - art. D666-3-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691672", "@num": "D666-3-2", "#text": "Code de la santé publique - art. D666-3-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691675", "@num": "D666-3-3", "#text": "Code de la santé publique - art. D666-3-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691674", "@num": "D666-3-3", "#text": "Code de la santé publique - art. D666-3-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691677", "@num": "D666-3-4", "#text": "Code de la santé publique - art. D666-3-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691676", "@num": "D666-3-4", "#text": "Code de la santé publique - art. D666-3-4 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691679", "@num": "D666-3-5", "#text": "Code de la santé publique - art. D666-3-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691678", "@num": "D666-3-5", "#text": "Code de la santé publique - art. D666-3-5 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691682", "@num": "D666-4-1", "#text": "Code de la santé publique - art. D666-4-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691680", "@num": "D666-4-1", "#text": "Code de la santé publique - art. D666-4-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691681", "@num": "D666-4-1", "#text": "Code de la santé publique - art. D666-4-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691684", "@num": "D666-4-2", "#text": "Code de la santé publique - art. D666-4-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691683", "@num": "D666-4-2", "#text": "Code de la santé publique - art. D666-4-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691686", "@num": "D666-4-3", "#text": "Code de la santé publique - art. D666-4-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691685", "@num": "D666-4-3", "#text": "Code de la santé publique - art. D666-4-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691687", "@num": "D666-4-4", "#text": "Code de la santé publique - art. D666-4-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691688", "@num": "D666-4-5", "#text": "Code de la santé publique - art. 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D712-13-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692041", "@num": "D712-13-2", "#text": "Code de la santé publique - art. D712-13-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691865", "@num": "D712-13-3", "#text": "Code de la santé publique - art. D712-13-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691868", "@num": "D712-13-4", "#text": "Code de la santé publique - art. 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D712-13-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691872", "@num": "D712-13-6", "#text": "Code de la santé publique - art. D712-13-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691870", "@num": "D712-13-6", "#text": "Code de la santé publique - art. D712-13-6 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691871", "@num": "D712-13-6", "#text": "Code de la santé publique - art. D712-13-6 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691740", "@num": "D712-130", "#text": "Code de la santé publique - art. D712-130 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691741", "@num": "D712-131", "#text": "Code de la santé publique - art. D712-131 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691742", "@num": "D712-132", "#text": "Code de la santé publique - art. D712-132 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691743", "@num": "D712-133", "#text": "Code de la santé publique - art. D712-133 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691744", "@num": "D712-134", "#text": "Code de la santé publique - art. D712-134 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691745", "@num": "D712-135", "#text": "Code de la santé publique - art. D712-135 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691746", "@num": "D712-136", "#text": "Code de la santé publique - art. D712-136 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691747", "@num": "D712-137", "#text": "Code de la santé publique - art. D712-137 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691748", "@num": "D712-138", "#text": "Code de la santé publique - art. D712-138 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691749", "@num": "D712-139", "#text": "Code de la santé publique - art. D712-139 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692127", "@num": "D712-14", "#text": "Code de la santé publique - art. D712-14 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692125", "@num": "D712-14", "#text": "Code de la santé publique - art. 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D712-141 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692145", "@num": "D712-142", "#text": "Code de la santé publique - art. D712-142 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691752", "@num": "D712-143", "#text": "Code de la santé publique - art. D712-143 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691753", "@num": "D712-144", "#text": "Code de la santé publique - art. D712-144 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691754", "@num": "D712-145", "#text": "Code de la santé publique - art. D712-145 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691755", "@num": "D712-146", "#text": "Code de la santé publique - art. D712-146 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691756", "@num": "D712-147", "#text": "Code de la santé publique - art. D712-147 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691757", "@num": "D712-148", "#text": "Code de la santé publique - art. D712-148 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691758", "@num": "D712-149", "#text": "Code de la santé publique - art. D712-149 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691879", "@num": "D712-15", "#text": "Code de la santé publique - art. 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D712-152 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691762", "@num": "D712-153", "#text": "Code de la santé publique - art. D712-153 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691881", "@num": "D712-16", "#text": "Code de la santé publique - art. D712-16 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006691880", "@num": "D712-16", "#text": "Code de la santé publique - art. 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L152 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692412", "@num": "L152", "#text": "Code de la santé publique - art. L152 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692556", "@num": "L152-1", "#text": "Code de la santé publique - art. L152-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692565", "@num": "L152-10", "#text": "Code de la santé publique - art. L152-10 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692566", "@num": "L152-11", "#text": "Code de la santé publique - art. L152-11 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692567", "@num": "L152-12", "#text": "Code de la santé publique - art. L152-12 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692568", "@num": "L152-13", "#text": "Code de la santé publique - art. L152-13 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692569", "@num": "L152-14", "#text": "Code de la santé publique - art. L152-14 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692570", "@num": "L152-15", "#text": "Code de la santé publique - art. L152-15 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692571", "@num": "L152-16", "#text": "Code de la santé publique - art. L152-16 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692572", "@num": "L152-17", "#text": "Code de la santé publique - art. L152-17 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692573", "@num": "L152-18", "#text": "Code de la santé publique - art. L152-18 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692574", "@num": "L152-19", "#text": "Code de la santé publique - art. L152-19 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692557", "@num": "L152-2", "#text": "Code de la santé publique - art. L152-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692558", "@num": "L152-3", "#text": "Code de la santé publique - art. L152-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692559", "@num": "L152-4", "#text": "Code de la santé publique - art. L152-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692560", "@num": "L152-5", "#text": "Code de la santé publique - art. L152-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692561", "@num": "L152-6", "#text": "Code de la santé publique - art. L152-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692562", "@num": "L152-7", "#text": "Code de la santé publique - art. L152-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692563", "@num": "L152-8", "#text": "Code de la santé publique - art. L152-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692564", "@num": "L152-9", "#text": "Code de la santé publique - art. L152-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692414", "@num": "L153", "#text": "Code de la santé publique - art. L153 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692416", "@num": "L153", "#text": "Code de la santé publique - art. L153 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692415", "@num": "L153", "#text": "Code de la santé publique - art. 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L16 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692178", "@num": "L16", "#text": "Code de la santé publique - art. L16 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692428", "@num": "L160", "#text": "Code de la santé publique - art. L160 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692429", "@num": "L161", "#text": "Code de la santé publique - art. L161 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692430", "@num": "L161-1", "#text": "Code de la santé publique - art. 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L162-22 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692437", "@num": "L162-3", "#text": "Code de la santé publique - art. L162-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692436", "@num": "L162-3", "#text": "Code de la santé publique - art. L162-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692440", "@num": "L162-4", "#text": "Code de la santé publique - art. 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L162-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692441", "@num": "L162-5", "#text": "Code de la santé publique - art. L162-5 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692444", "@num": "L162-6", "#text": "Code de la santé publique - art. L162-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692443", "@num": "L162-6", "#text": "Code de la santé publique - art. L162-6 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692446", "@num": "L162-7", "#text": "Code de la santé publique - art. L162-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692445", "@num": "L162-7", "#text": "Code de la santé publique - art. L162-7 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692448", "@num": "L162-8", "#text": "Code de la santé publique - art. L162-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692447", "@num": "L162-8", "#text": "Code de la santé publique - art. L162-8 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692450", "@num": "L162-9", "#text": "Code de la santé publique - art. L162-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692449", "@num": "L162-9", "#text": "Code de la santé publique - art. L162-9 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692463", "@num": "L163", "#text": "Code de la santé publique - art. L163 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692462", "@num": "L163", "#text": "Code de la santé publique - art. L163 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692465", "@num": "L164", "#text": "Code de la santé publique - art. L164 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692464", "@num": "L164", "#text": "Code de la santé publique - art. L164 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692466", "@num": "L164-1", "#text": "Code de la santé publique - art. L164-1 (P)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692467", "@num": "L164-2", "#text": "Code de la santé publique - art. L164-2 (P)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692468", "@num": "L164-3", "#text": "Code de la santé publique - art. L164-3 (P)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692469", "@num": "L165", "#text": "Code de la santé publique - art. L165 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692470", "@num": "L165", "#text": "Code de la santé publique - art. L165 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692472", "@num": "L166", "#text": "Code de la santé publique - art. L166 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692471", "@num": "L166", "#text": "Code de la santé publique - art. L166 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692473", "@num": "L167", "#text": "Code de la santé publique - art. L167 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692474", "@num": "L168", "#text": "Code de la santé publique - art. 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L171 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692478", "@num": "L172", "#text": "Code de la santé publique - art. L172 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692479", "@num": "L173", "#text": "Code de la santé publique - art. L173 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692480", "@num": "L174", "#text": "Code de la santé publique - art. L174 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692481", "@num": "L175", "#text": "Code de la santé publique - art. 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L187 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692508", "@num": "L187", "#text": "Code de la santé publique - art. L187 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692512", "@num": "L188", "#text": "Code de la santé publique - art. L188 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692511", "@num": "L188", "#text": "Code de la santé publique - art. L188 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692510", "@num": "L188", "#text": "Code de la santé publique - art. 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L190 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CREATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692514", "@num": "L190", "#text": "Code de la santé publique - art. L190 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692515", "@num": "L190", "#text": "Code de la santé publique - art. L190 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692518", "@num": "L190-1", "#text": "Code de la santé publique - art. L190-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692517", "@num": "L190-1", "#text": "Code de la santé publique - art. 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L192 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692521", "@num": "L192", "#text": "Code de la santé publique - art. L192 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692522", "@num": "L192", "#text": "Code de la santé publique - art. L192 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692525", "@num": "L193", "#text": "Code de la santé publique - art. L193 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692524", "@num": "L193", "#text": "Code de la santé publique - art. 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L224 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692688", "@num": "L225", "#text": "Code de la santé publique - art. L225 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692689", "@num": "L226", "#text": "Code de la santé publique - art. L226 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692690", "@num": "L227", "#text": "Code de la santé publique - art. L227 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692691", "@num": "L228", "#text": "Code de la santé publique - art. L228 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692692", "@num": "L229", "#text": "Code de la santé publique - art. L229 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692189", "@num": "L23", "#text": "Code de la santé publique - art. L23 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692693", "@num": "L230", "#text": "Code de la santé publique - art. L230 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692694", "@num": "L231", "#text": "Code de la santé publique - art. L231 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692695", "@num": "L232", "#text": "Code de la santé publique - art. L232 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692696", "@num": "L233", "#text": "Code de la santé publique - art. L233 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692697", "@num": "L234", "#text": "Code de la santé publique - art. L234 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692698", "@num": "L235", "#text": "Code de la santé publique - art. L235 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692699", "@num": "L236", "#text": "Code de la santé publique - art. L236 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692700", "@num": "L237", "#text": "Code de la santé publique - art. L237 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692701", "@num": "L238", "#text": "Code de la santé publique - art. L238 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692702", "@num": "L239", "#text": "Code de la santé publique - art. 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L276 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692746", "@num": "L277", "#text": "Code de la santé publique - art. L277 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692747", "@num": "L278", "#text": "Code de la santé publique - art. L278 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692748", "@num": "L279", "#text": "Code de la santé publique - art. L279 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692202", "@num": "L28", "#text": "Code de la santé publique - art. 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L282 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692753", "@num": "L283", "#text": "Code de la santé publique - art. L283 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692752", "@num": "L283", "#text": "Code de la santé publique - art. L283 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692755", "@num": "L284", "#text": "Code de la santé publique - art. L284 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692754", "@num": "L284", "#text": "Code de la santé publique - art. L284 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692757", "@num": "L284-1", "#text": "Code de la santé publique - art. L284-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692756", "@num": "L284-1", "#text": "Code de la santé publique - art. L284-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692758", "@num": "L285", "#text": "Code de la santé publique - art. L285 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692759", "@num": "L286", "#text": "Code de la santé publique - art. L286 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692760", "@num": "L287", "#text": "Code de la santé publique - art. L287 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692761", "@num": "L288", "#text": "Code de la santé publique - art. L288 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692762", "@num": "L289", "#text": "Code de la santé publique - art. L289 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692203", "@num": "L29", "#text": "Code de la santé publique - art. L29 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692763", "@num": "L290", "#text": "Code de la santé publique - art. L290 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692764", "@num": "L291", "#text": "Code de la santé publique - art. L291 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692765", "@num": "L292", "#text": "Code de la santé publique - art. L292 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692766", "@num": "L293", "#text": "Code de la santé publique - art. 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L297 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692772", "@num": "L298", "#text": "Code de la santé publique - art. L298 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692773", "@num": "L299", "#text": "Code de la santé publique - art. L299 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692158", "@num": "L3", "#text": "Code de la santé publique - art. L3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692205", "@num": "L30", "#text": "Code de la santé publique - art. 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L369 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692234", "@num": "L37", "#text": "Code de la santé publique - art. L37 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693230", "@num": "L370", "#text": "Code de la santé publique - art. L370 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693008", "@num": "L371", "#text": "Code de la santé publique - art. L371 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693007", "@num": "L371", "#text": "Code de la santé publique - art. L371 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693010", "@num": "L371-1", "#text": "Code de la santé publique - art. L371-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693009", "@num": "L371-1", "#text": "Code de la santé publique - art. L371-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693011", "@num": "L372", "#text": "Code de la santé publique - art. L372 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693012", "@num": "L373", "#text": "Code de la santé publique - art. L373 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693015", "@num": "L374", "#text": "Code de la santé publique - art. L374 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693013", "@num": "L374", "#text": "Code de la santé publique - art. L374 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693014", "@num": "L374", "#text": "Code de la santé publique - art. L374 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693017", "@num": "L375", "#text": "Code de la santé publique - art. L375 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693016", "@num": "L375", "#text": "Code de la santé publique - art. L375 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693020", "@num": "L376", "#text": "Code de la santé publique - art. L376 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693018", "@num": "L376", "#text": "Code de la santé publique - art. L376 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693019", "@num": "L376", "#text": "Code de la santé publique - art. L376 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693021", "@num": "L376-1", "#text": "Code de la santé publique - art. L376-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693022", "@num": "L376-2", "#text": "Code de la santé publique - art. L376-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693023", "@num": "L376-3", "#text": "Code de la santé publique - art. L376-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693024", "@num": "L377", "#text": "Code de la santé publique - art. L377 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693026", "@num": "L378", "#text": "Code de la santé publique - art. L378 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693025", "@num": "L378", "#text": "Code de la santé publique - art. L378 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693028", "@num": "L379", "#text": "Code de la santé publique - art. L379 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693027", "@num": "L379", "#text": "Code de la santé publique - art. L379 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692235", "@num": "L38", "#text": "Code de la santé publique - art. L38 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693029", "@num": "L380", "#text": "Code de la santé publique - art. L380 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693030", "@num": "L381", "#text": "Code de la santé publique - art. L381 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693031", "@num": "L382", "#text": "Code de la santé publique - art. L382 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693032", "@num": "L383", "#text": "Code de la santé publique - art. L383 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693033", "@num": "L384", "#text": "Code de la santé publique - art. L384 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693034", "@num": "L385", "#text": "Code de la santé publique - art. L385 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693035", "@num": "L386", "#text": "Code de la santé publique - art. L386 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693036", "@num": "L387", "#text": "Code de la santé publique - art. L387 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693037", "@num": "L388", "#text": "Code de la santé publique - art. L388 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693038", "@num": "L389", "#text": "Code de la santé publique - art. L389 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692236", "@num": "L39", "#text": "Code de la santé publique - art. L39 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693039", "@num": "L390", "#text": "Code de la santé publique - art. L390 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693040", "@num": "L391", "#text": "Code de la santé publique - art. L391 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693041", "@num": "L392", "#text": "Code de la santé publique - art. L392 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693042", "@num": "L393", "#text": "Code de la santé publique - art. L393 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693043", "@num": "L394", "#text": "Code de la santé publique - art. L394 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693045", "@num": "L395", "#text": "Code de la santé publique - art. L395 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693046", "@num": "L396", "#text": "Code de la santé publique - art. L396 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693047", "@num": "L397", "#text": "Code de la santé publique - art. L397 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693048", "@num": "L398", "#text": "Code de la santé publique - art. L398 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693049", "@num": "L399", "#text": "Code de la santé publique - art. L399 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692159", "@num": "L4", "#text": "Code de la santé publique - art. L4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692237", "@num": "L40", "#text": "Code de la santé publique - art. L40 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693050", "@num": "L400", "#text": "Code de la santé publique - art. L400 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693051", "@num": "L401", "#text": "Code de la santé publique - art. L401 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693052", "@num": "L402", "#text": "Code de la santé publique - art. L402 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693053", "@num": "L403", "#text": "Code de la santé publique - art. L403 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693056", "@num": "L404", "#text": "Code de la santé publique - art. L404 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693054", "@num": "L404", "#text": "Code de la santé publique - art. L404 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693055", "@num": "L404", "#text": "Code de la santé publique - art. L404 (MMN)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693057", "@num": "L405", "#text": "Code de la santé publique - art. L405 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693058", "@num": "L406", "#text": "Code de la santé publique - art. L406 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693235", "@num": "L407", "#text": "Code de la santé publique - art. L407 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693233", "@num": "L407", "#text": "Code de la santé publique - art. L407 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693234", "@num": "L407", "#text": "Code de la santé publique - art. L407 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693059", "@num": "L408", "#text": "Code de la santé publique - art. L408 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693060", "@num": "L409", "#text": "Code de la santé publique - art. L409 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692238", "@num": "L41", "#text": "Code de la santé publique - art. L41 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693236", "@num": "L410", "#text": "Code de la santé publique - art. L410 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693061", "@num": "L410-1", "#text": "Code de la santé publique - art. L410-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693239", "@num": "L411", "#text": "Code de la santé publique - art. L411 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693238", "@num": "L411", "#text": "Code de la santé publique - art. L411 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693242", "@num": "L412", "#text": "Code de la santé publique - art. L412 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693241", "@num": "L412", "#text": "Code de la santé publique - art. L412 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693240", "@num": "L412", "#text": "Code de la santé publique - art. L412 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693062", "@num": "L413", "#text": "Code de la santé publique - art. L413 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693064", "@num": "L414", "#text": "Code de la santé publique - art. L414 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693063", "@num": "L414", "#text": "Code de la santé publique - art. L414 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693066", "@num": "L415", "#text": "Code de la santé publique - art. L415 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693068", "@num": "L416", "#text": "Code de la santé publique - art. L416 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693067", "@num": "L416", "#text": "Code de la santé publique - art. L416 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693069", "@num": "L417", "#text": "Code de la santé publique - art. L417 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693070", "@num": "L418", "#text": "Code de la santé publique - art. L418 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693071", "@num": "L419", "#text": "Code de la santé publique - art. L419 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692239", "@num": "L42", "#text": "Code de la santé publique - art. L42 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693072", "@num": "L420", "#text": "Code de la santé publique - art. L420 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693073", "@num": "L421", "#text": "Code de la santé publique - art. L421 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693074", "@num": "L422", "#text": "Code de la santé publique - art. L422 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693078", "@num": "L423", "#text": "Code de la santé publique - art. 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L472-12 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693216", "@num": "L472-13", "#text": "Code de la santé publique - art. L472-13 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693217", "@num": "L472-14", "#text": "Code de la santé publique - art. L472-14 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693218", "@num": "L472-15", "#text": "Code de la santé publique - art. L472-15 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693219", "@num": "L472-16", "#text": "Code de la santé publique - art. L472-16 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693220", "@num": "L472-17", "#text": "Code de la santé publique - art. L472-17 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693221", "@num": "L472-18", "#text": "Code de la santé publique - art. L472-18 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693222", "@num": "L472-19", "#text": "Code de la santé publique - art. L472-19 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693204", "@num": "L472-2", "#text": "Code de la santé publique - art. L472-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693223", "@num": "L472-20", "#text": "Code de la santé publique - art. L472-20 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693224", "@num": "L472-21", "#text": "Code de la santé publique - art. L472-21 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693225", "@num": "L472-22", "#text": "Code de la santé publique - art. L472-22 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693205", "@num": "L472-3", "#text": "Code de la santé publique - art. L472-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693206", "@num": "L472-4", "#text": "Code de la santé publique - art. L472-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693208", "@num": "L472-5", "#text": "Code de la santé publique - art. L472-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693209", "@num": "L472-6", "#text": "Code de la santé publique - art. L472-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693210", "@num": "L472-7", "#text": "Code de la santé publique - art. L472-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693211", "@num": "L472-8", "#text": "Code de la santé publique - art. L472-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693212", "@num": "L472-9", "#text": "Code de la santé publique - art. 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L482-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693283", "@num": "L482-8", "#text": "Code de la santé publique - art. L482-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693284", "@num": "L482-9", "#text": "Code de la santé publique - art. L482-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693291", "@num": "L483", "#text": "Code de la santé publique - art. L483 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693293", "@num": "L483-1", "#text": "Code de la santé publique - art. 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L486 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693297", "@num": "L487", "#text": "Code de la santé publique - art. L487 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693300", "@num": "L488", "#text": "Code de la santé publique - art. L488 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693301", "@num": "L489", "#text": "Code de la santé publique - art. L489 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692259", "@num": "L49", "#text": "Code de la santé publique - art. L49 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692258", "@num": "L49", "#text": "Code de la santé publique - art. L49 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693302", "@num": "L490", "#text": "Code de la santé publique - art. L490 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693303", "@num": "L490", "#text": "Code de la santé publique - art. L490 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693304", "@num": "L491", "#text": "Code de la santé publique - art. L491 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693305", "@num": "L491-1", "#text": "Code de la santé publique - art. L491-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693306", "@num": "L491-2", "#text": "Code de la santé publique - art. L491-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693308", "@num": "L491-3", "#text": "Code de la santé publique - art. L491-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693307", "@num": "L491-3", "#text": "Code de la santé publique - art. L491-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693310", "@num": "L491-4", "#text": "Code de la santé publique - art. L491-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693309", "@num": "L491-4", "#text": "Code de la santé publique - art. 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L504-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693355", "@num": "L504-3", "#text": "Code de la santé publique - art. L504-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693356", "@num": "L504-4", "#text": "Code de la santé publique - art. L504-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693358", "@num": "L504-5", "#text": "Code de la santé publique - art. 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L504-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693361", "@num": "L504-8", "#text": "Code de la santé publique - art. L504-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693363", "@num": "L504-9", "#text": "Code de la santé publique - art. L504-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693374", "@num": "L505", "#text": "Code de la santé publique - art. L505 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693373", "@num": "L505", "#text": "Code de la santé publique - art. L505 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693375", "@num": "L506", "#text": "Code de la santé publique - art. L506 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693376", "@num": "L506-1", "#text": "Code de la santé publique - art. L506-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693377", "@num": "L507", "#text": "Code de la santé publique - art. L507 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693378", "@num": "L508", "#text": "Code de la santé publique - art. L508 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693379", "@num": "L509", "#text": "Code de la santé publique - art. L509 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692262", "@num": "L51", "#text": "Code de la santé publique - art. L51 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692263", "@num": "L51-1", "#text": "Code de la santé publique - art. L51-1 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692265", "@num": "L51-2", "#text": "Code de la santé publique - art. L51-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692267", "@num": "L51-3", "#text": "Code de la santé publique - art. L51-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693381", "@num": "L510-1", "#text": "Code de la santé publique - art. L510-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693409", "@num": "L510-10", "#text": "Code de la santé publique - art. L510-10 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693410", "@num": "L510-11", "#text": "Code de la santé publique - art. L510-11 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693383", "@num": "L510-2", "#text": "Code de la santé publique - art. L510-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693382", "@num": "L510-2", "#text": "Code de la santé publique - art. L510-2 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693384", "@num": "L510-3", "#text": "Code de la santé publique - art. L510-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693385", "@num": "L510-4", "#text": "Code de la santé publique - art. L510-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693386", "@num": "L510-5", "#text": "Code de la santé publique - art. L510-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693388", "@num": "L510-6", "#text": "Code de la santé publique - art. L510-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693387", "@num": "L510-6", "#text": "Code de la santé publique - art. L510-6 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693389", "@num": "L510-7", "#text": "Code de la santé publique - art. L510-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693390", "@num": "L510-8", "#text": "Code de la santé publique - art. L510-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693412", "@num": "L511", "#text": "Code de la santé publique - art. L511 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693411", "@num": "L511", "#text": "Code de la santé publique - art. L511 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693416", "@num": "L511-1", "#text": "Code de la santé publique - art. 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L511-3 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693420", "@num": "L511-4", "#text": "Code de la santé publique - art. L511-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693425", "@num": "L512", "#text": "Code de la santé publique - art. L512 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693421", "@num": "L512", "#text": "Code de la santé publique - art. L512 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693424", "@num": "L512", "#text": "Code de la santé publique - art. L512 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693423", "@num": "L512", "#text": "Code de la santé publique - art. L512 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693422", "@num": "L512", "#text": "Code de la santé publique - art. L512 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693426", "@num": "L512-1", "#text": "Code de la santé publique - art. L512-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693427", "@num": "L512-2", "#text": "Code de la santé publique - art. L512-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693428", "@num": "L512-3", "#text": "Code de la santé publique - art. L512-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693431", "@num": "L513", "#text": "Code de la santé publique - art. L513 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693430", "@num": "L513", "#text": "Code de la santé publique - art. L513 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693429", "@num": "L513", "#text": "Code de la santé publique - art. L513 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693432", "@num": "L513-1", "#text": "Code de la santé publique - art. L513-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693437", "@num": "L514", "#text": "Code de la santé publique - art. L514 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693434", "@num": "L514", "#text": "Code de la santé publique - art. L514 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693436", "@num": "L514", "#text": "Code de la santé publique - art. 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L514-1 (MMN)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693440", "@num": "L514-2", "#text": "Code de la santé publique - art. L514-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693441", "@num": "L515", "#text": "Code de la santé publique - art. L515 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693443", "@num": "L516", "#text": "Code de la santé publique - art. L516 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693444", "@num": "L517", "#text": "Code de la santé publique - art. L517 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693446", "@num": "L518", "#text": "Code de la santé publique - art. L518 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693445", "@num": "L518", "#text": "Code de la santé publique - art. L518 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693447", "@num": "L519", "#text": "Code de la santé publique - art. L519 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692272", "@num": "L52", "#text": "Code de la santé publique - art. L52 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693449", "@num": "L520", "#text": "Code de la santé publique - art. L520 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693448", "@num": "L520", "#text": "Code de la santé publique - art. L520 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693450", "@num": "L521", "#text": "Code de la santé publique - art. L521 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693451", "@num": "L522", "#text": "Code de la santé publique - art. L522 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693452", "@num": "L523", "#text": "Code de la santé publique - art. L523 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693453", "@num": "L524", "#text": "Code de la santé publique - art. L524 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693456", "@num": "L525", "#text": "Code de la santé publique - art. L525 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693455", "@num": "L525", "#text": "Code de la santé publique - art. 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L617-18 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693857", "@num": "L617-18", "#text": "Code de la santé publique - art. L617-18 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693854", "@num": "L617-18", "#text": "Code de la santé publique - art. L617-18 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693861", "@num": "L617-19", "#text": "Code de la santé publique - art. 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L617-20 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693866", "@num": "L617-21", "#text": "Code de la santé publique - art. L617-21 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693865", "@num": "L617-21", "#text": "Code de la santé publique - art. L617-21 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006693868", "@num": "L617-22", "#text": "Code de la santé publique - art. 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L797 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695276", "@num": "L798", "#text": "Code de la santé publique - art. L798 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695277", "@num": "L799", "#text": "Code de la santé publique - art. L799 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692164", "@num": "L8", "#text": "Code de la santé publique - art. L8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692386", "@num": "L80", "#text": "Code de la santé publique - art. 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L803 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695283", "@num": "L804", "#text": "Code de la santé publique - art. L804 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695284", "@num": "L805", "#text": "Code de la santé publique - art. L805 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695285", "@num": "L806", "#text": "Code de la santé publique - art. L806 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695286", "@num": "L807", "#text": "Code de la santé publique - art. L807 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695287", "@num": "L808", "#text": "Code de la santé publique - art. L808 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695288", "@num": "L809", "#text": "Code de la santé publique - art. L809 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692387", "@num": "L81", "#text": "Code de la santé publique - art. L81 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695289", "@num": "L810", "#text": "Code de la santé publique - art. L810 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695290", "@num": "L811", "#text": "Code de la santé publique - art. L811 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695291", "@num": "L812", "#text": "Code de la santé publique - art. L812 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695292", "@num": "L813", "#text": "Code de la santé publique - art. L813 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695293", "@num": "L814", "#text": "Code de la santé publique - art. L814 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695295", "@num": "L815", "#text": "Code de la santé publique - art. L815 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695296", "@num": "L816", "#text": "Code de la santé publique - art. L816 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695297", "@num": "L817", "#text": "Code de la santé publique - art. L817 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695298", "@num": "L818", "#text": "Code de la santé publique - art. L818 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695300", "@num": "L819", "#text": "Code de la santé publique - art. L819 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692388", "@num": "L82", "#text": "Code de la santé publique - art. L82 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695304", "@num": "L820", "#text": "Code de la santé publique - art. L820 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695305", "@num": "L821", "#text": "Code de la santé publique - art. L821 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695307", "@num": "L822", "#text": "Code de la santé publique - art. L822 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695309", "@num": "L823", "#text": "Code de la santé publique - art. L823 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695310", "@num": "L824", "#text": "Code de la santé publique - art. L824 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695311", "@num": "L825", "#text": "Code de la santé publique - art. L825 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695312", "@num": "L826", "#text": "Code de la santé publique - art. L826 (V)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695313", "@num": "L827", "#text": "Code de la santé publique - art. L827 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695314", "@num": "L828", "#text": "Code de la santé publique - art. L828 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695315", "@num": "L829", "#text": "Code de la santé publique - art. L829 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692389", "@num": "L83", "#text": "Code de la santé publique - art. L83 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695316", "@num": "L830", "#text": "Code de la santé publique - art. L830 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695317", "@num": "L831", "#text": "Code de la santé publique - art. L831 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695318", "@num": "L832", "#text": "Code de la santé publique - art. L832 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695319", "@num": "L833", "#text": "Code de la santé publique - art. L833 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695320", "@num": "L834", "#text": "Code de la santé publique - art. L834 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695322", "@num": "L835", "#text": "Code de la santé publique - art. L835 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695323", "@num": "L836", "#text": "Code de la santé publique - art. L836 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695324", "@num": "L837", "#text": "Code de la santé publique - art. L837 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695325", "@num": "L838", "#text": "Code de la santé publique - art. L838 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695326", "@num": "L839", "#text": "Code de la santé publique - art. L839 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692390", "@num": "L84", "#text": "Code de la santé publique - art. L84 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695327", "@num": "L840", "#text": "Code de la santé publique - art. L840 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695328", "@num": "L841", "#text": "Code de la santé publique - art. L841 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695329", "@num": "L842", "#text": "Code de la santé publique - art. L842 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695330", "@num": "L843", "#text": "Code de la santé publique - art. L843 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695331", "@num": "L844", "#text": "Code de la santé publique - art. L844 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695332", "@num": "L845", "#text": "Code de la santé publique - art. L845 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695333", "@num": "L846", "#text": "Code de la santé publique - art. L846 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695334", "@num": "L847", "#text": "Code de la santé publique - art. L847 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695335", "@num": "L848", "#text": "Code de la santé publique - art. L848 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695336", "@num": "L849", "#text": "Code de la santé publique - art. L849 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692391", "@num": "L85", "#text": "Code de la santé publique - art. L85 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695337", "@num": "L850", "#text": "Code de la santé publique - art. L850 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695339", "@num": "L851", "#text": "Code de la santé publique - art. L851 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695341", "@num": "L852", "#text": "Code de la santé publique - art. L852 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695342", "@num": "L853", "#text": "Code de la santé publique - art. L853 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695343", "@num": "L854", "#text": "Code de la santé publique - art. L854 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695344", "@num": "L855", "#text": "Code de la santé publique - art. L855 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695346", "@num": "L856", "#text": "Code de la santé publique - art. L856 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695348", "@num": "L857", "#text": "Code de la santé publique - art. L857 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695349", "@num": "L858", "#text": "Code de la santé publique - art. L858 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695350", "@num": "L859", "#text": "Code de la santé publique - art. L859 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006692392", "@num": "L86", "#text": "Code de la santé publique - art. L86 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695351", "@num": "L860", "#text": "Code de la santé publique - art. L860 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695352", "@num": "L861", "#text": "Code de la santé publique - art. L861 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695354", "@num": "L862", "#text": "Code de la santé publique - art. L862 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695355", "@num": "L863", "#text": "Code de la santé publique - art. L863 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695356", "@num": "L864", "#text": "Code de la santé publique - art. L864 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695357", "@num": "L865", "#text": "Code de la santé publique - art. L865 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695358", "@num": "L866", "#text": "Code de la santé publique - art. L866 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695376", "@num": "L867", "#text": "Code de la santé publique - art. L867 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695359", "@num": "L868", "#text": "Code de la santé publique - art. L868 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006695360", "@num": "L869", "#text": "Code de la santé publique - art. 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R180-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798841", "@num": "R180-30", "#text": "Code de la santé publique - art. R180-30 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798842", "@num": "R180-31", "#text": "Code de la santé publique - art. R180-31 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798843", "@num": "R180-32", "#text": "Code de la santé publique - art. R180-32 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798811", "@num": "R180-4", "#text": "Code de la santé publique - art. R180-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798812", "@num": "R180-5", "#text": "Code de la santé publique - art. R180-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798813", "@num": "R180-6", "#text": "Code de la santé publique - art. R180-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798814", "@num": "R180-7", "#text": "Code de la santé publique - art. R180-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798815", "@num": "R180-8", "#text": "Code de la santé publique - art. R180-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798816", "@num": "R180-9", "#text": "Code de la santé publique - art. R180-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798844", "@num": "R184-1-1", "#text": "Code de la santé publique - art. R184-1-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798854", "@num": "R184-1-10", "#text": "Code de la santé publique - art. R184-1-10 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798855", "@num": "R184-1-11", "#text": "Code de la santé publique - art. R184-1-11 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798857", "@num": "R184-1-12", "#text": "Code de la santé publique - art. R184-1-12 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798858", "@num": "R184-1-13", "#text": "Code de la santé publique - art. R184-1-13 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798859", "@num": "R184-1-14", "#text": "Code de la santé publique - art. R184-1-14 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798860", "@num": "R184-1-15", "#text": "Code de la santé publique - art. R184-1-15 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798845", "@num": "R184-1-2", "#text": "Code de la santé publique - art. R184-1-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798846", "@num": "R184-1-3", "#text": "Code de la santé publique - art. R184-1-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798848", "@num": "R184-1-4", "#text": "Code de la santé publique - art. R184-1-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798849", "@num": "R184-1-5", "#text": "Code de la santé publique - art. R184-1-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798850", "@num": "R184-1-6", "#text": "Code de la santé publique - art. R184-1-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798851", "@num": "R184-1-7", "#text": "Code de la santé publique - art. R184-1-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798852", "@num": "R184-1-8", "#text": "Code de la santé publique - art. R184-1-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798853", "@num": "R184-1-9", "#text": "Code de la santé publique - art. R184-1-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798861", "@num": "R184-2-1", "#text": "Code de la santé publique - art. R184-2-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798862", "@num": "R184-2-2", "#text": "Code de la santé publique - art. R184-2-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798863", "@num": "R184-2-3", "#text": "Code de la santé publique - art. R184-2-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798864", "@num": "R184-2-4", "#text": "Code de la santé publique - art. R184-2-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798866", "@num": "R184-3-1", "#text": "Code de la santé publique - art. R184-3-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798878", "@num": "R184-3-10", "#text": "Code de la santé publique - art. R184-3-10 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798877", "@num": "R184-3-10", "#text": "Code de la santé publique - art. R184-3-10 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798879", "@num": "R184-3-11", "#text": "Code de la santé publique - art. R184-3-11 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798880", "@num": "R184-3-12", "#text": "Code de la santé publique - art. R184-3-12 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798881", "@num": "R184-3-13", "#text": "Code de la santé publique - art. R184-3-13 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798882", "@num": "R184-3-14", "#text": "Code de la santé publique - art. R184-3-14 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798883", "@num": "R184-3-15", "#text": "Code de la santé publique - art. R184-3-15 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798884", "@num": "R184-3-16", "#text": "Code de la santé publique - art. R184-3-16 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798886", "@num": "R184-3-17", "#text": "Code de la santé publique - art. R184-3-17 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798887", "@num": "R184-3-18", "#text": "Code de la santé publique - art. R184-3-18 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798888", "@num": "R184-3-19", "#text": "Code de la santé publique - art. R184-3-19 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798867", "@num": "R184-3-2", "#text": "Code de la santé publique - art. R184-3-2 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798889", "@num": "R184-3-20", "#text": "Code de la santé publique - art. R184-3-20 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798868", "@num": "R184-3-3", "#text": "Code de la santé publique - art. R184-3-3 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798869", "@num": "R184-3-4", "#text": "Code de la santé publique - art. R184-3-4 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798870", "@num": "R184-3-5", "#text": "Code de la santé publique - art. R184-3-5 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798871", "@num": "R184-3-6", "#text": "Code de la santé publique - art. R184-3-6 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798872", "@num": "R184-3-7", "#text": "Code de la santé publique - art. R184-3-7 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798875", "@num": "R184-3-8", "#text": "Code de la santé publique - art. R184-3-8 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798876", "@num": "R184-3-9", "#text": "Code de la santé publique - art. R184-3-9 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798890", "@num": "R2001", "#text": "Code de la santé publique - art. R2001 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798892", "@num": "R2002", "#text": "Code de la santé publique - art. R2002 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798891", "@num": "R2002", "#text": "Code de la santé publique - art. R2002 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798894", "@num": "R2003", "#text": "Code de la santé publique - art. R2003 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798893", "@num": "R2003", "#text": "Code de la santé publique - art. R2003 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798897", "@num": "R2004", "#text": "Code de la santé publique - art. R2004 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798899", "@num": "R2005", "#text": "Code de la santé publique - art. R2005 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798898", "@num": "R2005", "#text": "Code de la santé publique - art. R2005 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798900", "@num": "R2006", "#text": "Code de la santé publique - art. R2006 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798902", "@num": "R2007", "#text": "Code de la santé publique - art. R2007 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798901", "@num": "R2007", "#text": "Code de la santé publique - art. R2007 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798904", "@num": "R2008", "#text": "Code de la santé publique - art. R2008 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798903", "@num": "R2008", "#text": "Code de la santé publique - art. R2008 (M)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798905", "@num": "R2009", "#text": "Code de la santé publique - art. R2009 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798906", "@num": "R2010", "#text": "Code de la santé publique - art. R2010 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798907", "@num": "R2011", "#text": "Code de la santé publique - art. R2011 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798908", "@num": "R2011-1", "#text": "Code de la santé publique - art. R2011-1 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798911", "@num": "R2012", "#text": "Code de la santé publique - art. R2012 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665", "@typelien": "CODIFICATION", "@naturetexte": "CODE", "@datesignatexte": "2999-01-01" }, { "@id": "LEGIARTI000006798913", "@num": "R2013", "#text": "Code de la santé publique - art. R2013 (Ab)", "@sens": "cible", "@cidtexte": "LEGITEXT000006072665",

Article R5118 AUTONOME MODIFIE, en vigueur du 28/11/1956 au 08/05/1988 (Code de la santé publique)